Matthew J Thomas
Overview
Explore the profile of Matthew J Thomas including associated specialties, affiliations and a list of published articles.
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65
Citations
2029
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Recent Articles
1.
Bammert M, Ansari M, Haag L, Ahmad Z, Schroder V, Birch J, et al.
Adv Sci (Weinh)
. 2024 Dec;
12(5):e2406751.
PMID: 39676507
Idiopathic pulmonary fibrosis (IPF) is a lethal disease with substantial unmet medical needs. While aberrant epithelial remodeling is a key factor in IPF progression, the molecular mechanisms behind this process...
2.
Millette T, Ramcharitar R, Monfredi O, Thomas M, Conaway M, Dean P
Med Sci Sports Exerc
. 2024 Oct;
57(2):260-266.
PMID: 39352231
Introduction: Patients with heritable thoracic aortic disease (HTAD) are often restricted from sports and certain types of exercise. This study was designed to investigate the effect of lifetime exercise exposure...
3.
Moiseenko A, Sinadinos A, Sergijenko A, Pineault K, Saleh A, Nekola K, et al.
Eur Respir J
. 2024 Aug;
65(1).
PMID: 39174284
Rationale And Objective: Cystic fibrosis (CF) is caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. CFTR modulators offer significant improvements, but ∼10% of patients remain nonresponsive or...
4.
Mayr C, Santacruz D, Jarosch S, Bleck M, Dalton J, McNabola A, et al.
Sci Adv
. 2024 Aug;
10(32):eadl5473.
PMID: 39121212
Despite advancements in antifibrotic therapy, idiopathic pulmonary fibrosis (IPF) remains a medical condition with unmet needs. Single-cell RNA sequencing (scRNA-seq) has enhanced our understanding of IPF but lacks the cellular...
5.
Nizamoglu M, Alleblas F, Koster T, Borghuis T, Vonk J, Thomas M, et al.
Acta Biomater
. 2024 Feb;
177:118-131.
PMID: 38350556
Idiopathic pulmonary fibrosis (IPF), for which effective treatments are limited, results in excessive and disorganized deposition of aberrant extracellular matrix (ECM). An altered ECM microenvironment is postulated to contribute to...
6.
Weckerle J, Mayr C, Fundel-Clemens K, Lammle B, Boryn L, Thomas M, et al.
Am J Respir Cell Mol Biol
. 2023 Jul;
69(4):422-440.
PMID: 37411041
Bleomycin-induced pulmonary fibrosis in mice mimics major hallmarks of idiopathic pulmonary fibrosis. Yet in this model, it spontaneously resolves over time. We studied molecular mechanisms of fibrosis resolution and lung...
7.
Watson C, Schloesser D, Fundel-Clemens K, Lerner C, Gabler S, Baskaran P, et al.
Am J Respir Cell Mol Biol
. 2022 Oct;
68(4):366-380.
PMID: 36227799
Profibrotic and prohomeostatic macrophage phenotypes remain ill-defined, both and , impeding the successful development of drugs that reprogram macrophages as an attractive therapeutic approach to manage fibrotic disease. The goal...
8.
Radwanska A, Cottage C, Piras A, Overed-Sayer C, Sihlbom C, Budida R, et al.
JCI Insight
. 2022 Aug;
7(16).
PMID: 35993367
Idiopathic pulmonary fibrosis (IPF) is a chronic disease of unmet medical need. It is characterized by formation of scar tissue leading to a progressive and irreversible decline in lung function....
9.
Mumby S, Kermani N, Garnett J, Pavlidis S, Wilson S, Howarth P, et al.
Allergy
. 2022 Aug;
77(11):3463-3466.
PMID: 35916059
No abstract available.
10.
Fry D, Groepper D, MacCarrick G, Demo E, Thomas M, Wilkes M, et al.
Am J Med Genet A
. 2022 Apr;
188(7):2237-2241.
PMID: 35426477
Loeys-Dietz syndrome (LDS) is a connective tissue disorder that commonly results in a dilated aorta, aneurysms, joint laxity, craniosynostosis, and soft skin that bruises easily. Neurodevelopmental abnormalities are uncommon in...