Paulo J Oliveira
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Explore the profile of Paulo J Oliveira including associated specialties, affiliations and a list of published articles.
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298
Citations
4791
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Recent Articles
11.
Amorim R, Soares P, Chavarria D, Benfeito S, Cagide F, Teixeira J, et al.
Eur J Med Chem
. 2024 Aug;
277:116723.
PMID: 39163775
Non-alcoholic fatty liver disease (NAFLD) presents a pervasive global pandemic, affecting approximately 25 % of the world's population. This grave health issue not only demands urgent attention but also stands...
12.
Magalhaes M, Dominguez-Martin E, Jorge J, Goncalves A, Massenzio F, Spigarelli R, et al.
J Ethnopharmacol
. 2024 Aug;
335:118689.
PMID: 39128799
Ethnopharmacological Relevance: Glioblastoma (GB) is the most aggressive and prevalent glioma within the central nervous system. Despite considerable efforts, GB continues to exhibit a dismal 5-year survival rate (∼6%). This...
13.
Grilo L, Zimmerman K, Puppala S, Chan J, Huber H, Li G, et al.
Adv Sci (Weinh)
. 2024 Aug;
11(38):e2309211.
PMID: 39119859
Age is a prominent risk factor for cardiometabolic disease, often leading to heart structural and functional changes. However, precise molecular mechanisms underlying cardiac remodeling and dysfunction exclusively resulting from physiological...
14.
Pinto M, Silva T, Sardao V, Simoes R, Albuquerque B, Oliveira P, et al.
ACS Pharmacol Transl Sci
. 2024 May;
7(5):1637-1649.
PMID: 38751615
Nitrocatechols are the standard pharmacophore to develop potent tight-binding inhibitors of catechol -methyltransferase (COMT), which can be used as coadjuvant drugs to manage Parkinson's disease. Tolcapone is the most potent...
15.
Potes Y, Bermejo-Millo J, Mendes C, Castelao-Baptista J, Diaz-Luis A, Perez-Martinez Z, et al.
Cell Death Dis
. 2024 Mar;
15(3):200.
PMID: 38459002
During aging, muscle regenerative capacities decline, which is concomitant with the loss of satellite cells that enter in a state of irreversible senescence. However, what mechanisms are involved in myogenic...
16.
Cunha-Oliveira T, Ioannidis J, Oliveira P
Physiol Rev
. 2024 Mar;
104(3):1387-1408.
PMID: 38451234
Effective data management is crucial for scientific integrity and reproducibility, a cornerstone of scientific progress. Well-organized and well-documented data enable validation and building on results. Data management encompasses activities including...
17.
Ferreiro E, Monteiro M, Pereira F, Barroso C, Egas C, Macedo P, et al.
Mech Ageing Dev
. 2024 Jan;
218:111912.
PMID: 38266781
The global population over 60 years old is projected to reach 1.5 billion by 2050. Understanding age-related disorders and gender-specificities is crucial for a healthy aging. Reliable age-related biomarkers are...
18.
Amorim R, Magalhaes C, Benfeito S, Cagide F, Tavares L, Santos K, et al.
Biochem Pharmacol
. 2023 Nov;
219:115953.
PMID: 38036191
The pharmacological interest in mitochondria is very relevant since these crucial organelles are involved in the pathogenesis of multiple diseases, such as cancer. In order to modulate cellular redox/oxidative balance...
19.
Grilo L, Zimmerman K, Puppala S, Chan J, Huber H, Li G, et al.
bioRxiv
. 2023 Nov;
PMID: 38014295
Age is a prominent risk factor for cardiometabolic disease, and often leads to heart structural and functional changes. However, precise molecular mechanisms underlying cardiac remodeling and dysfunction resulting from physiological...
20.
Pinho A, Santos D, Oliveira P, Leal E, Carvalho E
Eur J Clin Invest
. 2023 Nov;
54(3):e14128.
PMID: 37975307
Introduction: Diabetes mellitus (DM) impairs wound healing. The aim was to determine whether DM influences mitochondrial respiration in wounded skin (WS) and non-wounded skin (NWS), in a pre-clinical wound healing...