Paulo F Santos
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Explore the profile of Paulo F Santos including associated specialties, affiliations and a list of published articles.
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24
Citations
345
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Recent Articles
1.
Santos P, Fazendeiro B, Luca F, Ambrosio A, Leger H
Eur J Cell Biol
. 2023 Jun;
102(2):151333.
PMID: 37327741
Nuclear Dbf2-related (NDR) kinases are a subgroup of evolutionarily conserved AGC protein kinases that regulate various aspects of cell growth and morphogenesis. There are 4 NDR protein kinases in mammals,...
2.
Boia R, Dias P, Galindo-Romero C, Ferreira H, Aires I, Vidal-Sanz M, et al.
J Control Release
. 2022 Feb;
343:469-481.
PMID: 35131370
Retinal ganglion cell (RGC) loss underlies several conditions which give rise to significant visual compromise, including glaucoma and ischaemic optic neuropathies. Neuroprotection of RGCs is a clinical well-defined unmet need...
3.
Matos A, Bruno D, Ambrosio A, Santos P
Nutrients
. 2020 Oct;
12(10).
PMID: 33081260
Diabetic retinopathy (DR), one of the most common complications of diabetes, is the leading cause of legal blindness among adults of working age in developed countries. After 20 years of...
4.
Graca V, Ferreira I, Santos P
Curr Pharm Des
. 2020 Jan;
26(16):1838-1865.
PMID: 31942856
Background: Plants from the Geranium genus, which comprises about 400 species, have been used since ancient times in the practice of traditional medicines throughout the world. Therefore, herbal preparations based...
5.
Mandim F, Barros L, Heleno S, Pires T, Dias M, Alves M, et al.
Food Funct
. 2019 May;
10(5):2399-2407.
PMID: 31049501
The phenolic profile and the antibacterial activity against pathogenic commensal vaginal bacteria exhibited by different fractions of the acetone extract of heather were assessed. The acetone extract of Calluna vulgaris...
6.
Mandim F, Graca V, Calhelha R, Machado I, Ferreira L, Ferreira I, et al.
Molecules
. 2019 Mar;
24(5).
PMID: 30823489
In this work, several benzothiazole-based aminosquaraine dyes, displaying strong absorption within the so-called phototherapeutic window (650⁻800 nm), were synthesized. The ability, of all the new dyes, to generate singlet oxygen...
7.
Magalhaes A, Graca V, Calhelha R, Ferreira Machado I, Vieira Ferreira L, Ferreira I, et al.
Photochem Photobiol Sci
. 2018 Oct;
18(2):336-342.
PMID: 30310913
Squaraine dyes have recently attracted interest as potential second generation photosensitizers for photodynamic therapy. Several cationic aminosquaraine dyes bearing benzoselenazole terminal nuclei were synthezised and their cytotoxic activity was tested...
8.
Rodrigues-Neves A, Aires I, Vindeirinho J, Boia R, Madeira M, Goncalves F, et al.
Front Pharmacol
. 2018 Feb;
9:16.
PMID: 29416510
Glaucoma is the second cause of blindness worldwide and is characterized by the degeneration of retinal ganglion cells (RGCs) and optic nerve atrophy. Increased microglia reactivity is an early event...
9.
Magalhaes A, Graca V, Calhelha R, Ferreira I, Santos P
Bioorg Med Chem Lett
. 2017 Aug;
27(18):4467-4470.
PMID: 28807437
The synthesis of several aminosquaraine cationic dyes displaying strong absorption within the so-called phototherapeutic window (650-850nm) is described. Their cytotoxicity, under dark and illuminated conditions, was tested against several human...
10.
Ferreira D, Conceicao D, Fernandes F, Sousa T, Calhelha R, Ferreira I, et al.
J Phys Chem B
. 2016 Feb;
120(7):1212-20.
PMID: 26829502
In this work, a squaraine dye CS5 was characterized and evaluated for its potential in photodynamic therapy. The studies were performed in ethanol and also in a powdered biopolymer, in...