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Paulo F Santos

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Articles 24
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Recent Articles
11.
Tanaka E, Santos P, Reis J, Rodrigues N, Moraes R, Abreu D
Braz J Phys Ther . 2015 Jun; 19(3):186-93. PMID: 26083602
Background: Risk of falls increases as age advances. Complaints of impaired balance are very common in the elderly age group. Objectives: The objective of this study was to investigate whether...
12.
Madeira M, Boia R, Santos P, Ambrosio A, Santiago A
Mediators Inflamm . 2015 Apr; 2015:673090. PMID: 25873768
Retinal degenerative diseases are major causes of vision loss and blindness worldwide and are characterized by chronic and progressive neuronal loss. One common feature of retinal degenerative diseases and brain...
13.
Graca V, Sousa F, Santos P, Almeida P
Methods Mol Biol . 2015 Mar; 1286:23-33. PMID: 25749942
Affinity chromatography (AC) is one of the most important techniques for the separation and purification of biomolecules, being probably the most selective technique for protein purification. It is based on...
14.
Silva M, Graca V, Reis L, Santos P, Silvestre S, Granadeiro L, et al.
J Sep Sci . 2015 Jan; 38(5):732-40. PMID: 25556997
Currently, in biomedicine and biotechnology fields, there is a growing need to develop and produce biomolecules with a high degree of purity. To accomplish this goal, new purification methods are...
15.
Santiago A, Baptista F, Santos P, Cristovao G, Ambrosio A, Cunha R, et al.
Mediators Inflamm . 2014 Aug; 2014:465694. PMID: 25132733
Neuroinflammation mediated by microglial cells in the brain has been commonly associated with neurodegenerative diseases. Whether this microglia-mediated neuroinflammation is cause or consequence of neurodegeneration is still a matter of...
16.
Vindeirinho J, Costa G, Correia M, Cavadas C, Santos P
PLoS One . 2013 Jul; 8(6):e67499. PMID: 23840723
The early stages of diabetic retinopathy (DR) are characterized by alterations similar to neurodegenerative and inflammatory conditions such as increased neural apoptosis, microglial cell activation and amplified production of pro-inflammatory...
17.
Vieira Ferreira L, Ferreira D, Duarte P, Oliveira A, Torres E, Ferreira Machado I, et al.
Int J Mol Sci . 2012 Feb; 13(1):596-611. PMID: 22312274
In this work, thia and selenocarbocyanines with n-alkyl chains of different length, namely with methyl, ethyl, propyl, hexyl and decyl substituents, were studied in homogeneous and heterogeneous media for comparison...
18.
Baptista F, Gaspar J, Cristovao A, Santos P, Kofalvi A, Ambrosio A
Brain Res . 2011 Feb; 1383:257-69. PMID: 21281613
Diabetes induces changes in neurotransmitter release in central nervous system, which depend on the type of neurotransmitter and region studied. In this study, we evaluated the effect of diabetes (two...
19.
Santiago A, Gaspar J, Baptista F, Cristovao A, Santos P, Kamphuis W, et al.
Mol Vis . 2009 Aug; 15:1620-30. PMID: 19693289
Purpose: Diabetic retinopathy (DR) is a leading cause of vision loss and blindness among adults between the age 20 to 74. Changes in ionotropic glutamate receptor subunit composition can affect...
20.
Volkova K, Kovalska V, Losytskyy M, Bento A, Reis L, Santos P, et al.
J Fluoresc . 2008 Jan; 18(5):877-82. PMID: 18204936
Series of squaraine benzothiazole and benzoselenazole dyes were studied as possible fluorescent probes for the detection of proteins, particularly albumins. It was shown that majority of the studied squaraines give...