Paula J Bartlett
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Explore the profile of Paula J Bartlett including associated specialties, affiliations and a list of published articles.
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18
Citations
272
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Recent Articles
1.
Dos Santos B, Mallaupoma L, Pecenin M, Mohanty A, Lu A, Bartlett P, et al.
Malar J
. 2025 Feb;
24(1):45.
PMID: 39953553
Background: Despite the strides made in recent decades, the resistance observed in existing antimalarial drugs, and the intricate life cycle of the Plasmodium parasite underscore the pressing need to develop...
2.
Velasquez A, Patino Linares I, Gaspers L, Bartlett P, Velasques J, Netto A, et al.
Int J Parasitol Drugs Drug Resist
. 2025 Jan;
27:100574.
PMID: 39746288
Leishmaniasis is a neglected disease that remains with a limited number of drugs available for chemotherapy and has an increased drug resistance that affects treatment outcomes. Metal-based drugs such as...
3.
Brumer R, Correa-Velloso J, Thomas S, Sandiford O, Thomas A, Bartlett P
J Physiol
. 2023 Mar;
601(8):1383-1405.
PMID: 36864773
Excess consumption of carbohydrates, fat and calories leads to non-alcoholic fatty liver disease (NAFLD) and hepatic insulin resistance; these are major factors in the pathogenesis of type II diabetes. Hormones...
4.
Correa-Velloso J, Bartlett P, Brumer R, Gaspers L, Ulrich H, Thomas A
iScience
. 2021 Oct;
24(10):103139.
PMID: 34646983
Extracellular agonists linked to inositol-1,4,5-trisphosphate (IP) formation elicit cytosolic Ca oscillations in many cell types, but despite a common signaling pathway, distinct agonist-specific Ca spike patterns are observed. Using qPCR,...
5.
Velasquez A, Bartlett P, Linares I, Passalacqua T, Teodoro D, Imamura K, et al.
Antimicrob Agents Chemother
. 2021 Oct;
66(1):e0076721.
PMID: 34633848
The current treatment of leishmaniasis is based on a few drugs that present several drawbacks, such as high toxicity, difficult administration route, and low efficacy. These disadvantages raise the necessity...
6.
Cloete I, Correa-Velloso J, Bartlett P, Kirk V, Thomas A, Sneyd J
J Theor Biol
. 2021 Feb;
518:110629.
PMID: 33607144
Calcium (Ca) oscillations in hepatocytes have a wide dynamic range. In particular, recent experimental evidence shows that agonist stimulation of the P2Y family of receptors leads to qualitatively diverse Ca...
7.
Gaspers L, Thomas A, Hoek J, Bartlett P
Function (Oxf)
. 2021 Feb;
2(2):zqab002.
PMID: 33604575
Receptor-coupled phospholipase C (PLC) is an important target for the actions of ethanol. In the ex vivo perfused rat liver, concentrations of ethanol >100 mM were required to induce a...
8.
Borges-Pereira L, Thomas S, Dos Anjos E Silva A, Bartlett P, Thomas A, Garcia C
J Biol Chem
. 2020 Aug;
295(44):14998-15012.
PMID: 32848018
Cytosolic Ca regulates multiple steps in the host-cell invasion, growth, proliferation, and egress of blood-stage , yet our understanding of Ca signaling in this endemic malaria parasite is incomplete. By...
9.
Cloete I, Bartlett P, Kirk V, Thomas A, Sneyd J
J Theor Biol
. 2020 Jul;
503:110390.
PMID: 32628939
Calcium (Ca) oscillations in hepatocytes control many critical cellular functions, including glucose metabolism and bile secretion. The mechanisms underlying repetitive Ca oscillations and how these mechanisms regulate these oscillations is...
10.
Bartlett P, Cloete I, Sneyd J, Thomas A
iScience
. 2020 May;
23(5):101062.
PMID: 32353764
Ca oscillations that depend on inositol-1,4,5-trisphosphate (IP) have been ascribed to biphasic Ca regulation of the IP receptor (IPR) or feedback mechanisms controlling IP levels in different cell types. IP...