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James Sneyd

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Articles 86
Citations 1124
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Recent Articles
1.
Castaneda Ruan P, Benson J, Trebak M, Kirk V, Sneyd J
Bull Math Biol . 2024 Jun; 86(7):86. PMID: 38869652
is a ubiquitous signaling mechanism across different cell types. In T-cells, it is associated with cytokine production and immune function. Benson et al. have shown the coexistence of competing oscillations...
2.
Su S, Wahl A, Rugis J, Suresh V, Yule D, Sneyd J
Am J Physiol Gastrointest Liver Physiol . 2024 Feb; 326(5):G555-G566. PMID: 38349781
Cystic fibrosis (CF) is a genetic disease caused by the mutations of cystic fibrosis transmembrane conductance regulator (), the cystic fibrosis transmembrane conductance regulator gene. Cftr is a critical ion...
3.
Lee L, Yoast R, Emrich S, Trebak M, Kirk V, Sneyd J
J Theor Biol . 2024 Jan; 581:111740. PMID: 38253220
The role of Ca release-activated Ca (CRAC) channels mediated by ORAI isoforms in calcium signalling has been extensively investigated. It has been shown that the presence or absence of different...
4.
Benson J, Romito O, Abdelnaby A, Xin P, Pathak T, Weir S, et al.
J Biol Chem . 2023 Oct; 299(11):105310. PMID: 37778728
T-cell receptor stimulation triggers cytosolic Ca signaling by inositol-1,4,5-trisphosphate (IP)-mediated Ca release from the endoplasmic reticulum (ER) and Ca entry through Ca release-activated Ca (CRAC) channels gated by ER-located stromal-interacting...
5.
Wahl A, Takano T, Su S, Warner B, Perez P, Sneyd J, et al.
J Physiol . 2023 Sep; 601(20):4539-4556. PMID: 37724716
Currently, all salivary ducts (intercalated, striated and collecting) are assumed to function broadly in a similar manner, reclaiming ions that were secreted by the secretory acinar cells while preserving fluid...
6.
Rugis J, Chaffer J, Sneyd J, Yule D
bioRxiv . 2023 Jul; PMID: 37398053
Calcium signaling data analysis has become increasing complex as the size of acquired datasets increases. In this paper we present a Ca signaling data analysis method that employs custom written...
7.
Zeng Z, Cheng M, Li M, Wang T, Wen F, Sanderson M, et al.
Front Cell Dev Biol . 2023 Jun; 11:1202573. PMID: 37346175
BALB/c and C57BL/6 mouse strains are widely used as animal model in studies of respiratory diseases, such as asthma. Asthma is characterized by airway hyperresponsiveness, which is eventually resulted from...
8.
Kazmierczak B, Sneyd J, Tsai J
Bull Math Biol . 2022 Dec; 85(1):10. PMID: 36585964
The existence and properties of intracellular waves of increased free cytoplasmic calcium concentration (calcium waves) are strongly affected by the binding and unbinding of calcium ions to a multitude of...
9.
Sneyd J, Rugis J, Su S, Suresh V, Wahl A, Yule D
Biomolecules . 2022 Oct; 12(10). PMID: 36291663
The cytosolic concentration of free calcium ions ([Ca2+]) is an important intracellular messenger in most cell types, and the spatial distribution of [Ca2+] is often critical. In a salivary gland...
10.
Su S, Rugis J, Wahl A, Doak S, Li Y, Suresh V, et al.
Bull Math Biol . 2022 Jul; 84(8):84. PMID: 35799078
Saliva is produced in two stages in the salivary glands: the secretion of primary saliva by the acinus and the modification of saliva composition to final saliva by the intercalated...