Paul Toselli
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Explore the profile of Paul Toselli including associated specialties, affiliations and a list of published articles.
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24
Citations
673
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Recent Articles
1.
Matsuura S, Mi R, Koupenova M, Eliades A, Patterson S, Toselli P, et al.
Blood
. 2016 Jan;
127(11):1493-501.
PMID: 26755713
Lysyl oxidase (LOX) is overexpressed in various pathologies associated with thrombosis, such as arterial stenosis and myeloproliferative neoplasms (MPNs). LOX is elevated in the megakaryocytic lineage of mouse models of...
2.
Biasini E, Unterberger U, Solomon I, Massignan T, Senatore A, Bian H, et al.
J Neurosci
. 2013 Feb;
33(6):2408-18.
PMID: 23392670
Growing evidence suggests that a physiological activity of the cellular prion protein (PrP(C)) plays a crucial role in several neurodegenerative disorders, including prion and Alzheimer's diseases. However, how the functional...
3.
Bergethon P, Kindler D, Hallock K, Blease S, Toselli P
Bioelectromagnetics
. 2013 Jan;
34(5):358-65.
PMID: 23322407
In normal development and pathology, the vascular system depends on complex interactions between cellular elements, biochemical molecules, and physical forces. The electrokinetic vascular streaming potential (EVSP) is an endogenous extremely...
4.
Gao S, Zhou J, Zhao Y, Toselli P, Li W
Toxicol Sci
. 2012 Nov;
132(2):379-89.
PMID: 23161664
Lysyl oxidase (LO) catalyzes crosslink of collagen, elastin, and histone H1, stabilizing the extracellular matrix and cell nucleus. This enzyme displays dual functions for tumorigenesis, i.e., as a tumor suppressor...
5.
Iskratsch T, Reijntjes S, Dwyer J, Toselli P, Degano I, Dominguez I, et al.
Cell Mol Life Sci
. 2012 Oct;
70(5):893-908.
PMID: 23052206
Posttranslational modifications such as phosphorylation are universally acknowledged regulators of protein function. Recently we characterised a striated muscle-specific isoform of the formin FHOD3 that displays distinct subcellular targeting and protein...
6.
Zhao Y, Toselli P, Li W
Int J Environ Res Public Health
. 2012 Apr;
9(2):474-95.
PMID: 22470304
To understand mechanisms for arsenic toxicity in the lung, we examined effects of sodium m-arsenite (As³⁺) on microtubule (MT) assembly in vitro (0-40 µM), in cultured rat lung fibroblasts (RFL6,...
7.
Dominguez I, Degano I, Chea K, Cha J, Toselli P, Seldin D
Mol Cell Biochem
. 2011 Jul;
356(1-2):209-16.
PMID: 21761203
CK2 is a highly conserved serine-threonine kinase involved in biological processes such as embryonic development, circadian rhythms, inflammation, and cancer. Biochemical experiments have implicated CK2 in the control of several...
8.
Yu J, Taylor L, Rich C, Toselli P, Stone P, Green D, et al.
J Cell Physiol
. 2011 Jul;
227(5):2013-21.
PMID: 21751211
The angiotensin II (AngII) type I receptor (AT1) was modified by replacing its third intracellular loop and C-terminal tail with the corresponding regions from the bradykinin B2 receptor. Transgenic mice...
9.
Zhao Y, Chen L, Gao S, Toselli P, Stone P, Li W
Toxicology
. 2009 Nov;
267(1-3):60-9.
PMID: 19879314
Cadmium (Cd) inhalation can result in emphysema. Cd exposure of rat lung fibroblasts (RFL6) enhanced levels of metal scavenging thiols, e.g., metallothionein (MT) and glutathione (GSH), and the heavy chain...
10.
Seldin D, Lou D, Toselli P, Landesman-Bollag E, Dominguez I
Mol Cell Biochem
. 2008 Jul;
316(1-2):141-7.
PMID: 18594950
Protein kinase CK2 is a highly conserved and ubiquitous serine-threonine kinase. It is a tetrameric enzyme that is made up of two regulatory CK2beta subunits and two catalytic subunits, either...