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Paul Toselli

Explore the profile of Paul Toselli including associated specialties, affiliations and a list of published articles. Areas
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Articles 24
Citations 673
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Recent Articles
11.
Lou D, Dominguez I, Toselli P, Landesman-Bollag E, OBrien C, Seldin D
Mol Cell Biol . 2007 Oct; 28(1):131-9. PMID: 17954558
Protein kinase CK2 (formerly casein kinase II) is a highly conserved and ubiquitous serine/threonine kinase that is composed of two catalytic subunits (CK2alpha and/or CK2alpha') and two CK2beta regulatory subunits....
12.
Gao S, Zhao Y, Kong L, Toselli P, Chou I, Stone P, et al.
J Biol Chem . 2007 Jun; 282(35):25322-37. PMID: 17597074
Lysyl oxidase (LO) stabilizes the extracellular matrix by cross-linking collagen and elastin. To assess the transcriptional regulation of LO, we cloned the 5'-flanking region with 3,979 bp of the rat...
13.
Chou D, Zhao Y, Gao S, Chou I, Toselli P, Stone P, et al.
Toxicol Sci . 2007 Jun; 99(1):267-76. PMID: 17584760
To probe mechanisms of cadmium (Cd) damage to the lung extracellular matrix (ECM), we developed Cd-resistant (CdR) rat lung fibroblasts (RFL6) by incubation with graded concentrations of Cd. CdR cells...
14.
Huang Z, Yu J, Toselli P, Bhawan J, Sudireddy V, Taylor L, et al.
J Cell Physiol . 2007 Feb; 211(3):816-25. PMID: 17299793
When human embryonic stem (hES) cells were placed into suspension culture followed by culture on BD matrigel coated plates in the presence of medium conditioned by NIH-3T3 cells, they differentiated...
15.
Yang D, Zhang Y, Nguyen H, Koupenova M, Chauhan A, Makitalo M, et al.
J Clin Invest . 2006 Jul; 116(7):1913-23. PMID: 16823489
Adenosine has been described as playing a role in the control of inflammation, but it has not been certain which of its receptors mediate this effect. Here, we generated an...
16.
Zhao Y, Gao S, Chou I, Toselli P, Stone P, Li W
Toxicol Sci . 2006 Jan; 90(2):478-89. PMID: 16432278
Copper (Cu)-dependent lysyl oxidase (LO) catalyzes crosslinking of collagen and elastin stabilizing the extracellular matrix (ECM). Chronic inhalation of cadmium (Cd), a toxic metal, induces emphysema. To probe mechanisms of...
17.
Gao S, Chen K, Zhao Y, Rich C, Chen L, Li S, et al.
Toxicol Sci . 2005 Jun; 87(1):197-203. PMID: 15933228
Lysyl oxidase (LO) catalyzes crosslinking of collagen and elastin essential for maintaining the structural integrity of the lung extracellular matrix (ECM). To understand mechanisms of cigarette smoke (CS)-induced emphysema, we...
18.
Traish A, Toselli P, Jeong S, Kim N
J Androl . 2005 Feb; 26(2):242-8. PMID: 15713830
Androgens are deemed to be critical for the development, growth, and maintenance of penile tissue as well as for erectile function. Androgens are also reported to inhibit differentiation of stroma...
19.
Black L, Brewer K, Morris S, Schreiber B, Toselli P, Nugent M, et al.
J Appl Physiol (1985) . 2005 Jan; 98(4):1434-41. PMID: 15640390
Pulmonary emphysema and vessel wall aneurysms are diseases characterized by elastolytic damage to elastin fibers that leads to mechanical failure. To model this, neonatal rat aortic smooth muscle cells were...
20.
Hofmann C, Wang X, Sullivan C, Toselli P, Stone P, E McLean S, et al.
J Biol Chem . 2004 Dec; 280(9):7694-701. PMID: 15615710
B-Myb represses collagen gene transcription in vascular smooth muscle cells (SMCs) in vitro and in vivo. Here we sought to determine whether elastin is similarly repressed by B-Myb. Levels of...