Paul M Nguyen
Overview
Explore the profile of Paul M Nguyen including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
422
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0
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Recent Articles
1.
Low R, Fung K, Gao H, Preaudet A, Dagley L, Yousef J, et al.
Cell Death Differ
. 2023 Mar;
30(5):1400.
PMID: 36949280
No abstract available.
2.
Low R, Fung K, Gao H, Preaudet A, Dagley L, Yousef J, et al.
Cell Death Differ
. 2023 Feb;
30(5):1155-1165.
PMID: 36828915
Epithelial-mesenchymal transition (EMT) is a continuum that includes epithelial, partial EMT, and mesenchymal states, each of which is associated with cancer progression, invasive capabilities, and ultimately, metastasis. We used a...
3.
Low R, Lim W, Nguyen P, Lee B, Christie M, Burgess A, et al.
Cancers (Basel)
. 2021 Oct;
13(19).
PMID: 34638463
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid malignancies. While immortalized cancer cell lines and genetically engineered murine models have increased our understanding of PDAC tumorigenesis, they...
4.
Alvarez-Diaz S, Preaudet A, Samson A, Nguyen P, Fung K, Garnham A, et al.
Cell Death Differ
. 2020 Nov;
28(5):1466-1476.
PMID: 33230260
Chronic inflammation of the large intestine is associated with an increased risk of developing colorectal cancer (CRC), the second most common cause of cancer-related deaths worldwide. Necroptosis has emerged as...
5.
Metcalfe R, Aizel K, Zlatic C, Nguyen P, Morton C, Lio D, et al.
J Biol Chem
. 2020 Apr;
295(24):8285-8301.
PMID: 32332100
Interleukin (IL) 11 activates multiple intracellular signaling pathways by forming a complex with its cell surface α-receptor, IL-11Rα, and the β-subunit receptor, gp130. Dysregulated IL-11 signaling has been implicated in...
6.
Fung K, Nguyen P, Putoczki T
Adv Exp Med Biol
. 2020 Feb;
1240:59-72.
PMID: 32060888
Interleukin (IL)-18, a member of the IL-1 family of cytokines, has emerged as a key regulator of mucosal homeostasis within the gastrointestinal tract. Like other members of this family, IL-18...
7.
Nguyen P, Dagley L, Preaudet A, Lam N, Giam M, Fung K, et al.
Cell Death Differ
. 2019 Jul;
27(2):742-757.
PMID: 31296963
Gastrointestinal epithelial cells provide a selective barrier that segregates the host immune system from luminal microorganisms, thereby contributing directly to the regulation of homeostasis. We have shown that from early...
8.
Nguyen P, Abdirahman S, Putoczki T
Growth Factors
. 2019 Jun;
37(1-2):1-11.
PMID: 31161823
Interleukin (IL)-11 belongs to the IL-6 family of cytokines, discovered over 30 years ago. While early studies focused on the ability of IL-11 to stimulate megakaryocytopoiesis, the importance of this...
9.
Eissmann M, Dijkstra C, Wouters M, Baloyan D, Mouradov D, Nguyen P, et al.
Cancer Immunol Res
. 2018 Feb;
6(4):409-421.
PMID: 29463593
Interleukin 33 (IL33) is an inflammatory cytokine released during necrotic cell death. The epithelium and stroma of the intestine express large amounts of IL33 and its receptor St2. IL33 is...
10.
Nguyen P, Putoczki T
Cytokine
. 2018 Feb;
118:8-18.
PMID: 29396054
Chronic inflammation is recognized as a key tumor-promoting factor in a number of epithelial cancers, including gastric cancer (GC). The production of pro-inflammatory cytokines in the tumor microenvironment by both...