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Paul M Krzyzanowski

Explore the profile of Paul M Krzyzanowski including associated specialties, affiliations and a list of published articles. Areas
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Articles 25
Citations 1350
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Recent Articles
1.
Isaev K, Liu T, Bakhtiari M, Tong K, Goswami R, Lam B, et al.
Haematologica . 2022 Jun; 108(1):196-206. PMID: 35734926
Intratumoral heterogeneity (ITH) provides the substrate for tumor evolution and treatment resistance, yet is remarkably understudied in lymphoma, due to the often limited amount of tissue that gets sampled during...
2.
OKane G, Grunwald B, Jang G, Masoomian M, Picardo S, Grant R, et al.
Clin Cancer Res . 2022 Jun; 28(12):2715. PMID: 35694787
No abstract available.
3.
Ferreira V, Chruscinski A, Kulasingam V, Pugh T, Dus T, Wouters B, et al.
PLoS One . 2021 Feb; 16(2):e0247258. PMID: 33592074
Health care workers (HCWs) are at higher risk for SARS-CoV-2 infection and may play a role in transmitting the infection to vulnerable patients and members of the community. This is...
4.
Zaidi S, Harrison T, Phipps A, Steinfelder R, Trinh Q, Qu C, et al.
Nat Commun . 2020 Jul; 11(1):3644. PMID: 32686686
Colorectal cancer (CRC) is a biologically heterogeneous disease. To characterize its mutational profile, we conduct targeted sequencing of 205 genes for 2,105 CRC cases with survival data. Our data shows...
5.
OKane G, Grunwald B, Jang G, Masoomian M, Picardo S, Grant R, et al.
Clin Cancer Res . 2020 Mar; 26(18):4901-4910. PMID: 32156747
Purpose: To determine the impact of basal-like and classical subtypes in advanced pancreatic ductal adenocarcinoma (PDAC) and to explore GATA6 expression as a surrogate biomarker. Experimental Design: Within the COMPASS...
6.
Chan-Seng-Yue M, Kim J, Wilson G, Ng K, Figueroa E, OKane G, et al.
Nat Genet . 2020 Feb; 52(4):463. PMID: 32051610
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
7.
Chan-Seng-Yue M, Kim J, Wilson G, Ng K, Figueroa E, OKane G, et al.
Nat Genet . 2020 Jan; 52(2):231-240. PMID: 31932696
Pancreatic adenocarcinoma presents as a spectrum of a highly aggressive disease in patients. The basis of this disease heterogeneity has proved difficult to resolve due to poor tumor cellularity and...
8.
Kim J, Zuzarte P, Murphy T, Chan-Seng-Yue M, Brown A, Krzyzanowski P, et al.
Leukemia . 2019 Aug; 34(1):306-311. PMID: 31435024
No abstract available.
9.
Zhou Z, Kalatskaya I, Russell D, Marcon N, Cirocco M, Krzyzanowski P, et al.
Clin Exp Gastroenterol . 2019 Jun; 12:219-229. PMID: 31190949
The incidence of esophageal adenocarcinoma (EAC) has increased by 700% in Western countries over the last 30 years. Although clinical guidelines call for endoscopic surveillance for EAC among high-risk populations,...
10.
Krzyzanowski P, Sircoulomb F, Yousif F, Normand J, La Rose J, Francis K, et al.
Sci Rep . 2019 Mar; 9(1):3590. PMID: 30837567
Genomic rearrangements are a hallmark of cancer biology and progression, allowing cells to rapidly transform through alterations in regulatory structures, changes in expression patterns, reprogramming of signaling pathways, and creation...