Paul M Krzyzanowski
Overview
Explore the profile of Paul M Krzyzanowski including associated specialties, affiliations and a list of published articles.
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25
Citations
1350
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0
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Recent Articles
11.
Egyud M, Sridhar P, Devaiah A, Yamada E, Saunders S, Stahlberg A, et al.
Head Neck
. 2018 Dec;
41(5):1351-1358.
PMID: 30554450
Background: Recommendations for perioperative therapy in head and neck cancer are not explicit and recurrence occurs frequently. Circulating tumor DNA is an emerging cancer biomarker, but has not been extensively...
12.
Kuczynski E, Krueger J, Chow A, Xu P, Man S, Sundaravadanam Y, et al.
Mol Cancer Ther
. 2018 Feb;
17(4):869-882.
PMID: 29483207
A recurring historic finding in cancer drug development is encouraging antitumor effects observed in tumor-bearing mice that fail to translate into the clinic. An intriguing exception to this pattern is...
13.
Aung K, Fischer S, Denroche R, Jang G, Dodd A, Creighton S, et al.
Clin Cancer Res
. 2017 Dec;
24(6):1344-1354.
PMID: 29288237
To perform real-time whole genome sequencing (WGS) and RNA sequencing (RNASeq) of advanced pancreatic ductal adenocarcinoma (PDAC) to identify predictive mutational and transcriptional features for better treatment selection. Patients with...
14.
Stahlberg A, Krzyzanowski P, Egyud M, Filges S, Stein L, Godfrey T
Nat Protoc
. 2017 Mar;
12(4):664-682.
PMID: 28253235
Detection of extremely rare variant alleles within a complex mixture of DNA molecules is becoming increasingly relevant in many areas of clinical and basic research, such as the detection of...
15.
Stahlberg A, Krzyzanowski P, Jackson J, Egyud M, Stein L, Godfrey T
Nucleic Acids Res
. 2016 Apr;
44(11):e105.
PMID: 27060140
Detection of cell-free DNA in liquid biopsies offers great potential for use in non-invasive prenatal testing and as a cancer biomarker. Fetal and tumor DNA fractions however can be extremely...
16.
Braunstein M, Liao L, Lyttle N, Lobo N, Taylor K, Krzyzanowski P, et al.
Breast Cancer Res
. 2016 Feb;
18(1):16.
PMID: 26852132
Background: Drug resistance in breast cancer is the major obstacle to effective treatment with chemotherapy. While upregulation of multidrug resistance genes is an important component of drug resistance mechanisms in...
17.
Borozan I, Wilson S, Blanchette P, Laflamme P, Watt S, Krzyzanowski P, et al.
BMC Bioinformatics
. 2012 Aug;
13:206.
PMID: 22901030
Background: It is now well established that nearly 20% of human cancers are caused by infectious agents, and the list of human oncogenic pathogens will grow in the future for...
18.
Marcotte R, Brown K, Suarez F, Sayad A, Karamboulas K, Krzyzanowski P, et al.
Cancer Discov
. 2012 May;
2(2):172-189.
PMID: 22585861
Unlabelled: Genomic analyses are yielding a host of new information on the multiple genetic abnormalities associated with specific types of cancer. A comprehensive description of cancer-associated genetic abnormalities can improve...
19.
Krzyzanowski P, Muro E, Andrade-Navarro M
Wiley Interdiscip Rev RNA
. 2012 May;
3(4):567-79.
PMID: 22555938
New developments are being brought to the field of molecular biology with the mounting evidence that RNA transcripts not translated into protein (noncoding RNAs, ncRNAs) hold a variety of biological...
20.
Levaot N, Voytyuk O, Dimitriou I, Sircoulomb F, Chandrakumar A, Deckert M, et al.
Cell
. 2011 Dec;
147(6):1324-39.
PMID: 22153076
Cherubism is an autosomal-dominant syndrome characterized by inflammatory destructive bony lesions resulting in symmetrical deformities of the facial bones. Cherubism is caused by mutations in Sh3bp2, the gene that encodes...