Paul Hakimpour
Overview
Explore the profile of Paul Hakimpour including associated specialties, affiliations and a list of published articles.
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6
Citations
779
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Recent Articles
1.
Sinclair C, Bommakanti G, Gardinassi L, Loebbermann J, Johnson M, Hakimpour P, et al.
Science
. 2017 Aug;
357(6355):1014-1021.
PMID: 28798047
Antigen-presenting cells (APCs) occupy diverse anatomical tissues, but their tissue-restricted homeostasis remains poorly understood. Here, working with mouse models of inflammation, we found that mechanistic target of rapamycin (mTOR)-dependent metabolic...
2.
Ravindran R, Loebbermann J, Nakaya H, Khan N, Ma H, Gama L, et al.
Nature
. 2016 Mar;
531(7595):523-527.
PMID: 26982722
The integrated stress response (ISR) is a homeostatic mechanism by which eukaryotic cells sense and respond to stress-inducing signals, such as amino acid starvation. General controlled non-repressed (GCN2) kinase is...
3.
Oh J, Ravindran R, Chassaing B, Carvalho F, Maddur M, Bower M, et al.
Immunity
. 2014 Sep;
41(3):478-492.
PMID: 25220212
Systems biological analysis of immunity to the trivalent inactivated influenza vaccine (TIV) in humans revealed a correlation between early expression of TLR5 and the magnitude of the antibody response. Vaccination...
4.
Dunnick W, Collins J, Shi J, Westfield G, Fontaine C, Hakimpour P, et al.
J Exp Med
. 2009 Nov;
206(12):2613-23.
PMID: 19887393
Both class switch recombination (CSR) and somatic hypermutation (SHM) require transcription and the trans-acting factor activation-induced cytidine deaminase (AID), and must be up-regulated during antigen-dependent differentiation of B lymphocytes. To...
5.
Teng G, Hakimpour P, Landgraf P, Rice A, Tuschl T, Casellas R, et al.
Immunity
. 2008 May;
28(5):621-9.
PMID: 18450484
B lymphocytes perform somatic hypermutation and class-switch recombination (CSR) of the immunoglobulin locus to generate an antibody repertoire diverse in both affinity and function. These somatic diversification processes are catalyzed...
6.
Czarneski J, Berguer P, Bekinschtein P, Kim D, Hakimpour P, Wagner N, et al.
Eur J Immunol
. 2002 Mar;
32(4):945-56.
PMID: 11920560
Mouse mammary tumor virus (MMTV) is acquired by neonates through milk and first infects lymphocytes in Peyer's patches. We show here that newborn mice lacking beta7 integrin or L-selectin were...