Paul E OMaille
Overview
Explore the profile of Paul E OMaille including associated specialties, affiliations and a list of published articles.
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31
Citations
615
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Recent Articles
1.
Rebholz Z, Shewade L, Kaler K, Larose H, Schubot F, Tholl D, et al.
Protein Sci
. 2023 Mar;
32(5):e4634.
PMID: 36974623
Insects have evolved a chemical communication system using terpenoids, a structurally diverse class of specialized metabolites, previously thought to be exclusively produced by plants and microbes. Gene discovery, bioinformatics, and...
2.
Tholl D, Rebholz Z, Morozov A, OMaille P
Nat Prod Rep
. 2023 Mar;
40(4):766-793.
PMID: 36880348
Covering: up to the beginning of 2023Many animals release volatile or semi-volatile terpenes as semiochemicals in intra- and inter-specific interactions. Terpenes are important constituents of pheromones and serve as chemical...
3.
Ballal A, Laurendon C, Salmon M, Vardakou M, Cheema J, Defernez M, et al.
Mol Biol Evol
. 2020 Mar;
37(7):1907-1924.
PMID: 32119077
We explore sequence determinants of enzyme activity and specificity in a major enzyme family of terpene synthases. Most enzymes in this family catalyze reactions that produce cyclic terpenes-complex hydrocarbons widely...
4.
Hraber P, OMaille P, Silberfarb A, Davis-Anderson K, Generous N, McMahon B, et al.
Trends Biotechnol
. 2019 Aug;
38(1):113-127.
PMID: 31427097
Viral proteins evade host immune function by molecular mimicry, often achieved by short linear motifs (SLiMs) of three to ten consecutive amino acids (AAs). Motif mimicry tolerates mutations, evolves quickly...
5.
Midford P, Latendresse M, OMaille P, Karp P
Metabolites
. 2019 May;
9(5).
PMID: 31052521
Interpreting changes in metabolite abundance in response to experimental treatments or disease states remains a major challenge in metabolomics. Pathway Covering is a new algorithm that takes a list of...
6.
Cheema J, Faraldos J, OMaille P
Plant Sci
. 2017 Jan;
255:29-38.
PMID: 28131339
Epistasis, the interaction between mutations and the genetic background, is a pervasive force in evolution that is difficult to predict yet derives from a simple principle - biological systems are...
7.
Paley S, OMaille P, Weaver D, Karp P
BMC Bioinformatics
. 2016 Dec;
17(1):529.
PMID: 27964719
Background: Metabolic pathway diagrams are a classical way of visualizing a linked cascade of biochemical reactions. However, to understand some biochemical situations, viewing a single pathway is insufficient, whereas viewing...
8.
Nguyen T, Faraldos J, Vardakou M, Salmon M, OMaille P, Ro D
Biochem Biophys Res Commun
. 2016 Oct;
479(4):622-627.
PMID: 27697527
The Andes-endemic Barnadesioideae lineage is the oldest surviving and phylogenetically basal subfamily of the Asteraceae (Compositae), a prolific group of flowering plants with world-wide distribution (∼24,000 species) marked by a...
9.
Salmon M, Thimmappa R, Minto R, Melton R, Hughes R, OMaille P, et al.
Proc Natl Acad Sci U S A
. 2016 Jul;
113(30):E4407-14.
PMID: 27412861
Triterpenes are structurally complex plant natural products with numerous medicinal applications. They are synthesized through an origami-like process that involves cyclization of the linear 30 carbon precursor 2,3-oxidosqualene into different...
10.
Koo H, Vickery C, Xu Y, Louie G, OMaille P, Bowman M, et al.
J Antibiot (Tokyo)
. 2016 Jun;
69(7):524-33.
PMID: 27328867
The plant terpene synthase (TPS) family is responsible for the biosynthesis of a variety of terpenoid natural products possessing diverse biological functions. TPSs catalyze the ionization and, most commonly, rearrangement...