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Paul Delgado-Olguin

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Articles 53
Citations 2535
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Recent Articles
11.
Delgado-Olguin P, Oktaba K, Furlan-Magaril M
Front Genet . 2021 Aug; 12:734981. PMID: 34456981
No abstract available.
12.
Koike Y, Li B, Chen Y, Ganji N, Alganabi M, Miyake H, et al.
Bio Protoc . 2021 Apr; 11(5):e3937. PMID: 33796611
This protocol describes a novel technique to investigate the microcirculation dynamics underlying the pathology in the small intestine of neonatal mice using two-photon laser-scanning microscopy (TPLSM). Recent technological advances in...
13.
Mohan H, Lenis M, Laurette E, Tejada O, Sanghvi T, Leung K, et al.
EBioMedicine . 2020 Dec; 63:103167. PMID: 33341441
Background: Dolutegravir (DTG) is a preferred regimen for all people with HIV including pregnant women, but its effects on the fetus are not fully understood. Periconceptional exposure to DTG has...
14.
Ahmed A, Liang M, Chi L, Zhou Y, Sled J, Wilson M, et al.
Mol Metab . 2020 Nov; 43:101116. PMID: 33212270
Objective: Heart disease risk can be programmed by intrauterine exposure to obesity. Dysregulating key transcription factors in cardiac progenitors can cause subsequent adult-onset heart disease. In this study, we investigated...
15.
Koike Y, Li B, Ganji N, Zhu H, Miyake H, Chen Y, et al.
Nat Commun . 2020 Oct; 11(1):4950. PMID: 33009377
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants with high mortality rate, indicating the need for precision treatment. NEC is characterized by intestinal inflammation and ischemia, as well...
16.
Wong T, Ahmed A, Yang G, Maino E, Steiman S, Hyatt E, et al.
Dis Model Mech . 2020 Sep; 13(9). PMID: 32988972
Duchenne muscular dystrophy (DMD) is a life-threatening neuromuscular disease caused by the lack of dystrophin, resulting in progressive muscle wasting and locomotor dysfunctions. By adulthood, almost all patients also develop...
17.
Li B, Wu R, Horne R, Ahmed A, Lee D, Robinson S, et al.
Mol Nutr Food Res . 2020 Sep; 64(21):e2000519. PMID: 32926533
Scope: Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency and currently the leading cause of mortality in preterm infants. Recent studies show that human milk oligosaccharides (HMOs) reduce the frequency...
18.
Schroder A, Aitken K, Jiang J, Sidler M, Tolg C, Siebenaller A, et al.
FASEB J . 2020 Jan; 34(3):3594-3615. PMID: 31984552
Current and potential medical therapy for obstruction-induced myopathic bladder dysfunction (from benign prostatic hyperplasia or posterior urethral valves) focuses on symptoms. The persistent tissue pathology and dysfunction after release of...
19.
Chen Y, Koike Y, Chi L, Ahmed A, Miyake H, Li B, et al.
Dis Model Mech . 2019 Nov; 12(12). PMID: 31704804
Major risk factors for necrotizing enterocolitis (NEC) are formula feeding and prematurity; however, their pathogenic mechanisms are unknown. Here, we found that insufficient arginine/nitric oxide synthesis limits blood flow in...
20.
Li B, Lee C, Cadete M, Zhu H, Koike Y, Hock A, et al.
Cell Death Dis . 2019 Oct; 10(10):743. PMID: 31582728
Necrotizing enterocolitis (NEC) is a devastating neonatal disease characterized by acute intestinal injury. Intestinal stem cell (ISC) renewal is required for gut regeneration in response to acute injury. The Wnt/β-catenin...