Paul D Kingsley
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Explore the profile of Paul D Kingsley including associated specialties, affiliations and a list of published articles.
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40
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2149
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Recent Articles
1.
Zhao N, Michelucci A, Pietrangelo L, Malik S, Groom L, Leigh J, et al.
EMBO J
. 2024 Oct;
43(23):5941-5971.
PMID: 39420094
Tubular aggregate myopathy (TAM) is a heritable myopathy primarily characterized by progressive muscle weakness, elevated levels of creatine kinase (CK), hypocalcemia, exercise intolerance, and the presence of tubular aggregates (TAs)....
2.
Livada A, McGrath K, Malloy M, Li C, Ture S, Kingsley P, et al.
J Clin Invest
. 2024 Sep;
134(22).
PMID: 39302653
Lung megakaryocytes (Mks) are largely extravascular with an immune phenotype (1). Because bone marrow (BM) Mks are short lived, it has been assumed that extravascular lung Mks are constantly "seeded"...
3.
McGrath K, Koniski A, Murphy K, Getman M, An H, Schulz V, et al.
bioRxiv
. 2024 Feb;
PMID: 38370741
The limited proliferative capacity of erythroid precursors is a major obstacle to generate sufficient numbers of in vitro-derived red blood cells (RBC) for clinical purposes. We and others have determined...
4.
Yang Q, Kingsley P, Kozlowski D, Angerer R, Angerer L
Dev Growth Differ
. 2023 Jun;
35(2):139-151.
PMID: 37280843
We have determined the expression pattern of arylsulfatase in embryos of the sea urchin Strongylocentrotus purpuratus. Polyclonal antibodies raised against a fusion protein containing sequences encoded by SpARSI (Yang et...
5.
Nemkov T, Kingsley P, Dzieciatkowska M, Malik J, McGrath K, Hansen K, et al.
Blood Adv
. 2022 Feb;
6(10):3072-3089.
PMID: 35139174
Primitive erythropoiesis is a critical component of the fetal cardiovascular network and is essential for the growth and survival of the mammalian embryo. The need to rapidly establish a functional...
6.
Zhang Y, McGrath K, Ayoub E, Kingsley P, Yu H, Fegan K, et al.
Cell Rep
. 2021 Aug;
36(7):109562.
PMID: 34407416
Hematopoietic ontogeny consists of two broad programs: an initial hematopoietic stem cell (HSC)-independent program followed by HSC-dependent hematopoiesis that sequentially seed the fetal liver and generate blood cells. However, the...
7.
Jeffery N, Davidson C, Peslak S, Kingsley P, Nakamura Y, Palis J, et al.
Epigenetics Chromatin
. 2021 Jul;
14(1):37.
PMID: 34330317
Background: Condensation of chromatin prior to enucleation is an essential component of terminal erythroid maturation, and defects in this process are associated with inefficient erythropoiesis and anemia. However, the mechanisms...
8.
Cao J, ODay D, Pliner H, Kingsley P, Deng M, Daza R, et al.
Science
. 2020 Nov;
370(6518).
PMID: 33184181
The gene expression program underlying the specification of human cell types is of fundamental interest. We generated human cell atlases of gene expression and chromatin accessibility in fetal tissues. For...
9.
Fox S, Myers J, Davidson C, Getman M, Kingsley P, Frankiewicz N, et al.
Nat Commun
. 2020 Sep;
11(1):4544.
PMID: 32917861
Stratification of enhancers by signal strength in ChIP-seq assays has resulted in the establishment of super-enhancers as a widespread and useful tool for identifying cell type-specific, highly expressed genes and...
10.
Dege C, Fegan K, Creamer J, Berrien-Elliott M, Luff S, Kim D, et al.
Dev Cell
. 2020 Mar;
53(2):229-239.e7.
PMID: 32197069
Natural killer (NK) cells are a critical component of the innate immune system. However, their ontogenic origin has remained unclear. Here, we report that NK cell potential first arises from...