Paul A S Breslin
Overview
Explore the profile of Paul A S Breslin including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
69
Citations
2058
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Hanselman E, Harmon C, Deng D, Sywanycz S, Caronia L, Jiang P, et al.
Br J Pharmacol
. 2025 Feb;
PMID: 39999478
Background And Purpose: The human sweet taste receptor, TAS1R2-TAS1R3, conveys sweet taste in the mouth and may help regulate glucose metabolism throughout the body. Ibuprofen and naproxen are structurally similar...
2.
Harmon C, Ahmed O, Breslin P
J Agric Food Chem
. 2024 Oct;
PMID: 39352105
Amino acids are necessary for life, and many must be consumed because they cannot be endogenously synthesized. Typically, we eat them as proteins and peptides, which have little taste. However,...
3.
Flammer L, Ellis H, Rivers N, Caronia L, Ghidewon M, Christensen C, et al.
Br J Pharmacol
. 2024 May;
181(17):3282-3299.
PMID: 38745397
Background And Purpose: Many medications taste intensely bitter. The innate aversion to bitterness affects medical compliance, especially in children. There is a clear need to develop bitter blockers to suppress...
4.
Kochem M, Hanselman E, Breslin P
PLoS One
. 2024 May;
19(5):e0298239.
PMID: 38691547
The sweet taste receptor, TAS1R2-TAS1R3, is expressed in taste bud cells, where it conveys sweetness, and also in intestinal enteroendocrine cells, where it may facilitate glucose absorption and assimilation. In...
5.
Amado N, Hanselman E, Harmon C, Deng D, Alarcon S, Sharples A, et al.
Chem Senses
. 2024 Jan;
49.
PMID: 38197318
The savory or umami taste of the amino acid glutamate is synergistically enhanced by the addition of the purines inosine 5'-monophosphate (IMP) and guanosine 5'-monophosphate (GMP) disodium salt. We hypothesized...
6.
Frank H, Amato K, Trautwein M, Maia P, Liman E, Nichols L, et al.
Proc Biol Sci
. 2022 Feb;
289(1968):20211918.
PMID: 35135352
The evolutionary history of sour taste has been little studied. Through a combination of literature review and trait mapping on the vertebrate phylogenetic tree, we consider the origin of sour...
7.
Breslin P, Izumi A, Tharp A, Ohkuri T, Yokoo Y, Flammer L, et al.
PLoS One
. 2021 Oct;
16(10):e0256989.
PMID: 34614010
The taste stimulus glucose comprises approximately half of the commercial sugar sweeteners used today, whether in the form of the di-saccharide sucrose (glucose-fructose) or half of high-fructose corn syrup (HFCS)....
8.
Schwiebert E, Wang Y, Xi R, Choma K, Streiff J, Flammer L, et al.
Mol Pharmacol
. 2021 Apr;
99(5):319-327.
PMID: 33824185
Children have difficulty swallowing capsules. Yet, when presented with liquid formulations, children often reject oral medications due to their intense bitterness. Presently, effective strategies to identify methods, reagents, and tools...
9.
Hanselman E, Amado N, Breslin P
Curr Opin Physiol
. 2021 Mar;
20:126-133.
PMID: 33738372
Both short chain fatty acids (SCFAs) and long chain fatty acids (LCFAs) rely on free fatty acid receptors to signal their presence to the body, but their individual detection and...
10.
Harmon C, Deng D, Breslin P
Curr Opin Physiol
. 2021 Mar;
20:70-76.
PMID: 33738371
In addition to being responsible for bitter taste, type 2 taste receptors (T2Rs) regulate endocrine, behavioral, and immunological responses. T2R agonists include indicators of incoming threats to metabolic homeostasis, pathogens,...