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Patrick Tschopp

Explore the profile of Patrick Tschopp including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 580
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Recent Articles
1.
Wang M, Di Pietro-Torres A, Feregrino C, Luxey M, Moreau C, Fischer S, et al.
Nat Commun . 2025 Mar; 16(1):2187. PMID: 40038298
Cell type repertoires have expanded extensively in metazoan animals, with some clade-specific cells being crucial to evolutionary success. A prime example are the skeletogenic cells of vertebrates. Depending on anatomical...
2.
Sommer-Trembo C, Santos M, Clark B, Werner M, Fages A, Matschiner M, et al.
Science . 2024 Apr; 384(6694):470-475. PMID: 38662824
Behavior is critical for animal survival and reproduction, and possibly for diversification and evolutionary radiation. However, the genetics behind adaptive variation in behavior are poorly understood. In this work, we...
3.
Atsuta Y, Lee C, Rodrigues A, Colle C, Tomizawa R, Lujan E, et al.
Dev Cell . 2024 Feb; 59(3):415-430.e8. PMID: 38320485
The early limb bud consists of mesenchymal limb progenitors derived from the lateral plate mesoderm (LPM). The LPM also gives rise to the mesodermal components of the flank and neck....
4.
Grall E, Feregrino C, Fischer S, De Courten A, Sacher F, Hiscock T, et al.
Proc Natl Acad Sci U S A . 2024 Jan; 121(2):e2304470121. PMID: 38175868
Repeating patterns of synovial joints are a highly conserved feature of articulated digits, with variations in joint number and location resulting in diverse digit morphologies and limb functions across the...
5.
Luxey M, Stieger G, Berki B, Tschopp P
Front Cell Dev Biol . 2023 May; 11:1154205. PMID: 37215090
The tetrapod limb has long served as a paradigm to study vertebrate pattern formation and evolutionary diversification. The distal part of the limb, the so-called autopod, is of particular interest...
6.
Berki B, Sacher F, Fages A, Tschopp P, Luxey M
Dev Dyn . 2022 Jun; 252(1):208-219. PMID: 35705847
Background: Motor neurons in the vertebrate spinal cord have long served as a paradigm to study the transcriptional logic of cell type specification and differentiation. At limb levels, pool-specific transcriptional...
7.
Sacher F, Feregrino C, Tschopp P, Ewald C
Matrix Biol Plus . 2021 Jul; 10:100069. PMID: 34195598
Transcriptomic signatures based on cellular mRNA expression profiles can be used to categorize cell types and states. Yet whether different functional groups of genes perform better or worse in this...
8.
Feregrino C, Tschopp P
Dev Dyn . 2021 Jun; 251(9):1472-1489. PMID: 34114716
Background: During development, complex organ patterns emerge through the precise temporal and spatial specification of different cell types. On an evolutionary timescale, these patterns can change, resulting in morphological diversification....
9.
Grall E, Tschopp P
Dev Dyn . 2019 Nov; 249(3):313-327. PMID: 31702845
Fifty years ago, Lewis Wolpert introduced the concept of "positional information" to explain how patterns form in a multicellular embryonic field. Using morphogen gradients, whose continuous distributions of positional values...
10.
Luxey M, Berki B, Heusermann W, Fischer S, Tschopp P
Dev Biol . 2019 Nov; 458(2):133-140. PMID: 31697937
The tetrapod limb has long served as a paradigm to study vertebrate pattern formation. During limb morphogenesis, a number of distinct tissue types are patterned and subsequently must be integrated...