Jozsef Zakany
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Explore the profile of Jozsef Zakany including associated specialties, affiliations and a list of published articles.
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21
Citations
734
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Recent Articles
1.
Lopez-Delisle L, Zakany J, Bochaton C, Osteil P, Mayran A, Darbellay F, et al.
Proc Natl Acad Sci U S A
. 2024 Nov;
121(46):e2414865121.
PMID: 39499640
Mammalian tail length is controlled by several genetic determinants, among which are genes, whose function is to terminate the body axis. Accordingly, the precise timing in the transcriptional activation of...
2.
Amandio A, Beccari L, Lopez-Delisle L, Mascrez B, Zakany J, Gitto S, et al.
Genes Dev
. 2021 Oct;
35(21-22):1490-1509.
PMID: 34711654
Mammalian gene clusters contain a range of CTCF binding sites. In addition to their importance in organizing a TAD border, which isolates the most posterior genes from the rest of...
3.
Allais-Bonnet A, Hintermann A, Deloche M, Cornette R, Bardou P, Naval-Sanchez M, et al.
Mol Biol Evol
. 2021 Feb;
38(6):2260-2272.
PMID: 33528505
In the course of evolution, pecorans (i.e., higher ruminants) developed a remarkable diversity of osseous cranial appendages, collectively referred to as "headgear," which likely share the same origin and genetic...
4.
Darbellay F, Bochaton C, Lopez-Delisle L, Mascrez B, Tschopp P, Delpretti S, et al.
Proc Natl Acad Sci U S A
. 2019 Jun;
116(27):13424-13433.
PMID: 31209053
In many animal species with a bilateral symmetry, genes are clustered either at one or at several genomic loci. This organization has a functional relevance, as the transcriptional control applied...
5.
Zakany J, Duboule D
BMC Res Notes
. 2018 Mar;
11(1):193.
PMID: 29580290
Objective: We had previously reported a mouse line carrying the Atypical female courtship (HoxD ) allele, where an ectopic accumulation of Hoxd10 transcripts was observed in a sparse population of...
6.
Zakany J, Darbellay F, Mascrez B, Necsulea A, Duboule D
Proc Natl Acad Sci U S A
. 2017 Oct;
114(44):E9290-E9299.
PMID: 29042517
During embryonic development, genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this...
7.
Schep R, Necsulea A, Rodriguez-Carballo E, Guerreiro I, Andrey G, Huynh T, et al.
Proc Natl Acad Sci U S A
. 2016 Nov;
113(48):E7720-E7729.
PMID: 27856734
Vertebrate Hox genes encode transcription factors operating during the development of multiple organs and structures. However, the evolutionary mechanism underlying this remarkable pleiotropy remains to be fully understood. Here, we...
8.
Huang B, Trofka A, Furusawa A, Norrie J, Rabinowitz A, Vokes S, et al.
Nat Commun
. 2016 Oct;
7:12903.
PMID: 27713395
The number of phalanges and joints are key features of digit 'identity' and are central to limb functionality and evolutionary adaptation. Prior chick work indicated that digit phalanges and their...
9.
Lonfat N, Montavon T, Jebb D, Tschopp P, Huynh T, Zakany J, et al.
Proc Natl Acad Sci U S A
. 2013 Jul;
110(29):11946-51.
PMID: 23818637
When positioned into the integrin α-6 gene, an Hoxd9lacZ reporter transgene displayed parental imprinting in mouse embryos. While the expression from the paternal allele was comparable with patterns seen for...
10.
Zakany J, Duboule D
Curr Biol
. 2012 Aug;
22(18):1676-80.
PMID: 22863319
Although neural substrates of mammalian female mating behavior have been described, the association between complex courtship activity and specific underlying mechanisms remains elusive. We have isolated a mouse line that...