Sabrina Fischer
Overview
Explore the profile of Sabrina Fischer including associated specialties, affiliations and a list of published articles.
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22
Citations
205
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Recent Articles
1.
Wang M, Di Pietro-Torres A, Feregrino C, Luxey M, Moreau C, Fischer S, et al.
Nat Commun
. 2025 Mar;
16(1):2187.
PMID: 40038298
Cell type repertoires have expanded extensively in metazoan animals, with some clade-specific cells being crucial to evolutionary success. A prime example are the skeletogenic cells of vertebrates. Depending on anatomical...
2.
Simon C, Brunke I, Stielow B, Forne I, Steitz A, Geller M, et al.
PLoS Biol
. 2024 Aug;
22(8):e3002739.
PMID: 39137238
Pancreatic ductal adenocarcinoma (PDAC) poses a significant threat due to its tendency to evade early detection, frequent metastasis, and the subsequent challenges in devising effective treatments. Processes that govern epithelial-mesenchymal...
3.
Fischer S, Weber L, Stielow B, Frech M, Simon C, Geller M, et al.
Nucleic Acids Res
. 2024 May;
52(13):7590-7609.
PMID: 38801077
Acute myeloid leukemia (AML) is a hematological malignancy characterized by abnormal proliferation and accumulation of immature myeloid cells in the bone marrow. Inflammation plays a crucial role in AML progression,...
4.
Grall E, Feregrino C, Fischer S, De Courten A, Sacher F, Hiscock T, et al.
Proc Natl Acad Sci U S A
. 2024 Jan;
121(2):e2304470121.
PMID: 38175868
Repeating patterns of synovial joints are a highly conserved feature of articulated digits, with variations in joint number and location resulting in diverse digit morphologies and limb functions across the...
5.
Fischer S, Trinh V, Simon C, Weber L, Forne I, Nist A, et al.
Cell Chem Biol
. 2023 Jun;
30(7):766-779.e11.
PMID: 37354906
Inhibition of protein-protein interactions (PPIs) via designed peptides is an effective strategy to perturb their biological functions. The Elongin BC heterodimer (ELOB/C) binds to a BC-box motif and is essential...
6.
Fischer S, Liefke R
Genes (Basel)
. 2023 Apr;
14(4).
PMID: 37107696
Polycomb-like proteins (PCLs) are a crucial group of proteins associated with the Polycomb repressive complex 2 (PRC2) and are responsible for setting up the PRC2.1 subcomplex. In the vertebrate system,...
7.
Weber L, Jia Y, Stielow B, Gisselbrecht S, Cao Y, Ren Y, et al.
Nucleic Acids Res
. 2022 Dec;
51(2):574-594.
PMID: 36537216
The lysine acetyltransferase KAT6A (MOZ, MYST3) belongs to the MYST family of chromatin regulators, facilitating histone acetylation. Dysregulation of KAT6A has been implicated in developmental syndromes and the onset of...
8.
Simon C, Stielow B, Nist A, Rohner I, Weber L, Geller M, et al.
Biology (Basel)
. 2022 Apr;
11(4).
PMID: 35453756
The unmethylated CpG island-binding protein SAMD1 is upregulated in many human cancer types, but its cancer-related role has not yet been investigated. Here, we used the hepatocellular carcinoma cell line...
9.
Fischer S, Weber L, Liefke R
Epigenetics Chromatin
. 2022 Feb;
15(1):7.
PMID: 35193659
The Polycomb repressive complex 2 (PRC2) is an essential chromatin regulatory complex involved in repressing the transcription of diverse developmental genes. PRC2 consists of a core complex; possessing H3K27 methyltransferase...
10.
Liss F, Frech M, Wang Y, Giel G, Fischer S, Simon C, et al.
Cancers (Basel)
. 2021 Mar;
13(4).
PMID: 33673123
Personalized treatment of acute myeloid leukemia (AML) that target individual aberrations strongly improved the survival of AML patients. However, AML is still one of the most lethal cancer diseases of...