Patrick Munro
Overview
Explore the profile of Patrick Munro including associated specialties, affiliations and a list of published articles.
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Articles
26
Citations
539
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Recent Articles
1.
Garcia-Sanchez J, Bonnet E, Loubatier C, Doye A, Paillier G, Segui F, et al.
iScience
. 2025 Feb;
28(2):111838.
PMID: 39995862
Transcription factor EB (TFEB) is a key transcription factor that orchestrates the cellular response to stress. Dysregulation of TFEB is associated with a range of human diseases, and understanding the...
2.
Hachfi S, Brun-Barale A, Fichant A, Munro P, Nawrot-Esposito M, Michel G, et al.
Nat Commun
. 2024 Sep;
15(1):7733.
PMID: 39231950
Strains of the Bacillus cereus (Bc) group are sporulating bacteria commonly associated with foodborne outbreaks. Spores are dormant cells highly resistant to extreme conditions. Nevertheless, the pathological processes associated with...
3.
Doye A, Chaintreuil P, Lagresle-Peyrou C, Batistic L, Marion V, Munro P, et al.
J Exp Med
. 2024 Aug;
221(10).
PMID: 39212656
A growing number of patients presenting severe combined immunodeficiencies attributed to monoallelic RAC2 variants have been identified. The expression of the RHO GTPase RAC2 is restricted to the hematopoietic lineage....
4.
Munro P, Rekima S, Loubat A, Duranton C, Pisani D, Boyer L
PLoS One
. 2021 Aug;
16(8):e0256768.
PMID: 34437647
White adipocytes store energy differently than brown and brite adipocytes which dissipate energy under the form of heat. Studies have shown that adipocytes are able to respond to bacteria thanks...
5.
Courjon J, Dufies O, Robert A, Bailly L, Torre C, Chirio D, et al.
Blood Adv
. 2021 Mar;
5(5):1523-1534.
PMID: 33683342
Dysregulated immune response is the key factor leading to unfavorable coronavirus disease 2019 (COVID-19) outcome. Depending on the pathogen-associated molecular pattern, the NLRP3 inflammasome can play a crucial role during...
6.
Dufies O, Doye A, Courjon J, Torre C, Michel G, Loubatier C, et al.
Nat Microbiol
. 2021 Jan;
6(3):401-412.
PMID: 33432150
Inflammasomes are signalling platforms that are assembled in response to infection or sterile inflammation by cytosolic pattern recognition receptors. The consequent inflammasome-triggered caspase-1 activation is critical for the host defence...
7.
Munro P, Dufies O, Rekima S, Loubat A, Duranton C, Boyer L, et al.
Am J Physiol Endocrinol Metab
. 2020 Sep;
319(5):E912-E922.
PMID: 32954821
Numerous studies have shown that the recruitment and activation of thermogenic adipocytes, which are brown and beige/brite, reduce the mass of adipose tissue and normalize abnormal glycemia and lipidemia. However,...
8.
Colson C, Ghandour R, Dufies O, Rekima S, Loubat A, Munro P, et al.
Nutrients
. 2019 Feb;
11(2).
PMID: 30791540
Oxylipins are metabolized from dietary ω3 and ω6 polyunsaturated fatty acids and are involved in an inflammatory response. Adipose tissue inflammatory background is a key factor of metabolic disorders and...
9.
Bouillot S, Munro P, Gallet B, Reboud E, Cretin F, Golovkine G, et al.
Sci Rep
. 2017 May;
7(1):2120.
PMID: 28522850
Exolysin (ExlA) is a recently-identified pore-forming toxin secreted by a subset of Pseudomonas aeruginosa strains identified worldwide and devoid of Type III secretion system (T3SS), a major virulence factor. Here,...
10.
Michel G, Ferrua B, Munro P, Boyer L, Mathal N, Gillet D, et al.
PLoS One
. 2016 Jun;
11(6):e0156363.
PMID: 27257862
There is a need to develop new effective immunoadjuvants for prophylactic or therapeutic vaccines against intracellular pathogens. The activation of Rho GTPases by bacterial cytotoxic necrotizing factor 1 (CNF1) elicits...