Patrick Maschmeyer
Overview
Explore the profile of Patrick Maschmeyer including associated specialties, affiliations and a list of published articles.
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24
Citations
422
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Recent Articles
1.
Neumann C, Blume J, Roy U, Teh P, Vasanthakumar A, Beller A, et al.
Nat Immunol
. 2024 May;
25(7):1306.
PMID: 38783161
No abstract available.
2.
De Rop F, Hulselmans G, Flerin C, Soler-Vila P, Rafels A, Christiaens V, et al.
Nat Biotechnol
. 2023 Aug;
42(6):916-926.
PMID: 37537502
Single-cell assay for transposase-accessible chromatin by sequencing (scATAC-seq) has emerged as a powerful tool for dissecting regulatory landscapes and cellular heterogeneity. However, an exploration of systemic biases among scATAC-seq technologies...
3.
Lareau C, Dubois S, Buquicchio F, Hsieh Y, Garg K, Kautz P, et al.
Nat Genet
. 2023 Jun;
55(7):1198-1209.
PMID: 37386249
Pathogenic mutations in mitochondrial DNA (mtDNA) compromise cellular metabolism, contributing to cellular heterogeneity and disease. Diverse mutations are associated with diverse clinical phenotypes, suggesting distinct organ- and cell-type-specific metabolic vulnerabilities....
4.
Zhang X, Sharma P, Maschmeyer P, Hu Y, Lou M, Kim J, et al.
J Hepatol
. 2023 Jun;
79(5):1214-1225.
PMID: 37348791
Background & Aims: Glycoprotein A repetitions predominant (GARP) is a membrane protein that functions as a latent TGF-β docking molecule. While the immune regulatory properties of GARP on blood cells...
5.
Vanni A, Mazzoni A, Semeraro R, Capone M, Maschmeyer P, Lamacchia G, et al.
Eur J Immunol
. 2023 Apr;
53(7):e2250162.
PMID: 37086046
Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic condition in childhood. The disease etiology remains largely unknown; however, a key role in JIA pathogenesis is surely mediated by...
6.
Lutter L, Van Der Wal M, Brand E, Maschmeyer P, Vastert S, Mashreghi M, et al.
Clin Transl Immunology
. 2022 Oct;
11(10):e1420.
PMID: 36204213
Objective: Tregs are crucial for immune regulation, and environment-driven adaptation of effector (e)Tregs is essential for local functioning. However, the extent of human Treg heterogeneity in inflammatory settings is unclear....
7.
Maschmeyer P, Haas S
Mol Cell
. 2022 Jan;
82(2):234-236.
PMID: 35063091
Fiskin et al. (2021) developed a "multi-omics" approach that integrates phage-displayed single-domain antibodies ("nanobodies") with the assay for transposase-accessible chromatin (PHAGE-ATAC) to simultaneously determine protein expression, chromatin accessibility, and mitochondrial...
8.
Maschmeyer P, Zimmermann J, Kuhl A
Methods Mol Biol
. 2021 Apr;
2285:349-373.
PMID: 33928564
Inflammatory bowel disease (IBD) is a group of severe chronic inflammatory conditions of the human gastrointestinal tract. Murine models of colitis have been invaluable tools to improve the understanding of...
9.
Maschmeyer P, Chang H, Cheng Q, Mashreghi M, Hiepe F, Alexander T, et al.
Nat Rev Rheumatol
. 2021 Apr;
17(5):291-305.
PMID: 33824526
Why do we still have no cure for chronic inflammatory diseases? One reason could be that current therapies are based on the assumption that chronic inflammation is driven by persistent...
10.
Maschmeyer P, Heinz G, Skopnik C, Lutter L, Mazzoni A, Heinrich F, et al.
Eur J Immunol
. 2020 Dec;
51(4):915-929.
PMID: 33296081
T lymphocytes accumulate in inflamed tissues of patients with chronic inflammatory diseases (CIDs) and express pro-inflammatory cytokines upon re-stimulation in vitro. Further, a significant genetic linkage to MHC genes suggests...