Patrick L McGeer
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Explore the profile of Patrick L McGeer including associated specialties, affiliations and a list of published articles.
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136
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5694
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Recent Articles
1.
McGeer P, Lee M, Kennedy K, McGeer E
J Clin Med
. 2020 Feb;
9(2).
PMID: 32019214
Background: Saliva, the most readily available body fluid, is the product of genes which are in constant activity throughout life. Measurement of saliva can predict the onset of some diseases...
2.
Huang Z, Scotland K, Li Y, Guo J, McGeer P, Lange D, et al.
Electrophoresis
. 2019 Dec;
41(3-4):183-193.
PMID: 31850545
In this paper, the development of a simple dilute-and-shoot method for quantifying urinary creatinine by CE-ESI-MS was described. The creatinine analysis time was about 7 min/sample by conventional single injection...
3.
McGeer P, McGeer E
J Alzheimers Dis
. 2018 Mar;
64(s1):S361-S363.
PMID: 29562519
The means are now at hand to conquer Alzheimer's disease (AD). The method is to identify those at risk for the disease before clinical signs develop. That is followed by...
4.
McGeer P, Guo J, Lee M, Kennedy K, McGeer E
J Alzheimers Dis
. 2017 Nov;
62(3):1219-1222.
PMID: 29103042
Alzheimer's disease (AD) is characterized by deposits of amyloid-β protein (Aβ) in brain which become foci of inflammation. Neurons are destroyed by this inflammatory process, leading to the cognitive deficits...
5.
Cao Y, Wang X, Shi X, Clee S, McGeer P, Wolf M, et al.
Angew Chem Int Ed Engl
. 2017 Oct;
56(49):15603-15606.
PMID: 29045760
A family of environment-sensitive shape-shifting molecules have been developed as flexible fluorescent (FlexFluor) dyes for biological imaging applications. These compounds feature a flexible bithiophene-based fluorophore that gives rise to different...
6.
De Lorenzi E, Chiari M, Colombo R, Cretich M, Sola L, Vanna R, et al.
J Alzheimers Dis
. 2017 Jul;
59(4):1213-1226.
PMID: 28731438
Background: Identifying physiologically relevant binding partners of amyloid-β (Aβ) that modulate in vivo fibril formation may yield new insights into Alzheimer's disease (AD) etiology. Human cathelicidin peptide, LL-37, is an...
7.
McGeer P, Lee M, McGeer E
Neurobiol Aging
. 2017 Jan;
52:12-22.
PMID: 28104543
Complement is the backbone of our innate immune system. It is of ancient evolutionary origin, being traced back to horseshoe crabs 350 million years ago. It consists today of more...
8.
Lee M, Guo J, Kennedy K, McGeer E, McGeer P
J Alzheimers Dis
. 2016 Oct;
55(3):1175-1182.
PMID: 27792013
We have developed a non-invasive method of diagnosing Alzheimer's disease (AD), which can also predict the risk of its future onset. It is based on measuring salivary levels of amyloid-β...
9.
McGeer P, Rogers J, McGeer E
J Alzheimers Dis
. 2016 Oct;
54(3):853-857.
PMID: 27716676
Two basic discoveries spurred research into inflammation as a driving force in the pathogenesis of Alzheimer's disease (AD). The first was the identification of activated microglia in association with the...
10.
Lee M, McGeer E, McGeer P
Neurobiol Aging
. 2016 Aug;
46:113-23.
PMID: 27479153
Epidemiologic studies indicate that coffee consumption reduces the risk of Parkinson's disease and Alzheimer's disease. To determine the factors involved, we examined the protective effects of coffee components. The test...