Patrick G Telmer
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Explore the profile of Patrick G Telmer including associated specialties, affiliations and a list of published articles.
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10
Citations
325
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Recent Articles
1.
Telmer P, Kelman M, Renaud J, Sumarah M, Garnham C
Toxins (Basel)
. 2022 Aug;
14(8).
PMID: 36006206
Fumonisin mycotoxins are a family of secondary metabolites produced by and related species, as well as some strains of . Fumonisin contamination of maize is a concern when grown under...
2.
Garnham C, Butler S, Telmer P, Black F, Renaud J, Sumarah M
J Agric Food Chem
. 2020 Nov;
68(47):13779-13790.
PMID: 33174732
Fumonisin contamination of maize damaged by and related species is a major problem when it is grown under warm and dry conditions. Consumption of fumonisin contaminated food and feed is...
3.
Berish R, Ali A, Telmer P, Ronald J, Leong H
Nat Rev Urol
. 2018 May;
15(7):403-421.
PMID: 29769644
Metastatic disease is the principal cause of prostate-cancer-related mortality. Our ability to accurately recapitulate the spread of prostate cancer to bone - the most common site of metastasis - is...
4.
Schwertfeger K, Cowman M, Telmer P, Turley E, McCarthy J
Front Immunol
. 2015 Jun;
6:236.
PMID: 26106384
Breast cancer-induced inflammation in the tumor reactive stroma supports invasion and malignant progression and is contributed to by a variety of host cells including macrophages and fibroblasts. Inflammation appears to...
5.
Gabriel M, Telmer P, Marsolais F
Planta
. 2011 Dec;
235(5):1013-22.
PMID: 22127737
Structural determinants responsible for the substrate preference of the potassium-independent (ASPGA1) and -dependent (ASPGB1) asparaginases from Arabidopsis thaliana have been investigated. Like ASPGA1, ASPGB1 was found to be catalytically active...
6.
Telmer P, Tolg C, McCarthy J, Turley E
Commun Integr Biol
. 2011 Jun;
4(2):182-5.
PMID: 21655434
The mechanisms responsible for the oncogenic effects of the hyaluronan (HA) receptor and mitotic spindle binding protein, RHAMM, are poorly understood. On one hand, extracellular RHAMM interacts with HA and...
7.
Tolg C, Hamilton S, Morningstar L, Zhang J, Zhang S, Esguerra K, et al.
J Biol Chem
. 2010 Jun;
285(34):26461-74.
PMID: 20558733
An oncogenic form of RHAMM (receptor for hyaluronan-mediated motility, mouse, amino acids 163-794 termed RHAMM(Delta163)) is a cell surface hyaluronan receptor and mitotic spindle protein that is highly expressed in...
8.
Gould A, Telmer P, Shilton B
Biochemistry
. 2009 Jul;
48(33):8051-61.
PMID: 19630440
ATP hydrolysis by the maltose transporter (MalFGK(2)) is regulated by maltose binding protein (MBP). Binding of maltose to MBP brings about a conformational change from open to closed that leads...
9.
Telmer P, Shilton B
J Mol Biol
. 2005 Nov;
354(4):829-40.
PMID: 16288781
Protein engineering was used previously to convert maltose-binding protein (MBP) into a zinc biosensor. Zn(2+) binding by the engineered MBP was thought to require a large conformational change from "open"...
10.
Telmer P, Shilton B
J Biol Chem
. 2003 Jun;
278(36):34555-67.
PMID: 12794084
The affinity of maltose-binding protein (MBP) for maltose and related carbohydrates was greatly increased by removal of groups in the interface opposite the ligand binding cleft. The wild-type protein has...