Christopher P Garnham
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Explore the profile of Christopher P Garnham including associated specialties, affiliations and a list of published articles.
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25
Citations
749
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0
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Recent Articles
1.
Hoogstra S, Hendricks K, McMullin D, Renaud J, Bora J, Sumarah M, et al.
Toxins (Basel)
. 2024 Sep;
16(9).
PMID: 39330862
Zearalenone and radicicol are resorcylic acid lactones produced by numerous plant pathogenic fungi. Zearalenone is a non-steroidal estrogen mimic that can cause serious reproductive issues in livestock that consume contaminated...
2.
VanderBurgt J, Harper O, Garnham C, Kohalmi S, Menassa R
Front Plant Sci
. 2023 Feb;
14:1044675.
PMID: 36760639
Porcine reproductive and respiratory syndrome (PRRS) is a disease leading to spontaneous abortions and stillbirths in sows and lowered life quality and expectancy in growing pigs. PRRS is prevalent worldwide...
3.
Telmer P, Kelman M, Renaud J, Sumarah M, Garnham C
Toxins (Basel)
. 2022 Aug;
14(8).
PMID: 36006206
Fumonisin mycotoxins are a family of secondary metabolites produced by and related species, as well as some strains of . Fumonisin contamination of maize is a concern when grown under...
4.
Renaud J, DesRochers N, Hoogstra S, Garnham C, Sumarah M
Chem Res Toxicol
. 2021 Apr;
34(6):1604-1611.
PMID: 33891387
Fumonisins are mycotoxins produced by a number of species of and . They are polyketides that possess a linear polyol structure with two tricarballylic acid side chains and an amine...
5.
Garnham C, Butler S, Telmer P, Black F, Renaud J, Sumarah M
J Agric Food Chem
. 2020 Nov;
68(47):13779-13790.
PMID: 33174732
Fumonisin contamination of maize damaged by and related species is a major problem when it is grown under warm and dry conditions. Consumption of fumonisin contaminated food and feed is...
6.
Garnham C, Yu I, Li Y, Roll-Mecak A
Proc Natl Acad Sci U S A
. 2017 Jun;
114(25):6545-6550.
PMID: 28576883
Glycylation and glutamylation, the posttranslational addition of glycines and glutamates to genetically encoded glutamates in the intrinsically disordered tubulin C-terminal tails, are crucial for the biogenesis and stability of cilia...
7.
Garnham C, Vemu A, Wilson-Kubalek E, Yu I, Szyk A, Lander G, et al.
Cell
. 2015 May;
161(5):1112-1123.
PMID: 25959773
Glutamylation, the most prevalent tubulin posttranslational modification, marks stable microtubules and regulates recruitment and activity of microtubule- interacting proteins. Nine enzymes of the tubulin tyrosine ligase-like (TTLL) family catalyze glutamylation....
8.
Yu I, Garnham C, Roll-Mecak A
J Biol Chem
. 2015 May;
290(28):17163-72.
PMID: 25957412
Microtubules give rise to intracellular structures with diverse morphologies and dynamics that are crucial for cell division, motility, and differentiation. They are decorated with abundant and chemically diverse posttranslational modifications...
9.
Vemu A, Garnham C, Lee D, Roll-Mecak A
Methods Enzymol
. 2014 Mar;
540:149-66.
PMID: 24630106
Tubulin, the building block of microtubules, is subject to chemically diverse and evolutionarily conserved post-translational modifications that mark microtubules for specific functions in the cell. Here we describe in vitro...
10.
Basu K, Garnham C, Nishimiya Y, Tsuda S, Braslavsky I, Davies P
J Vis Exp
. 2014 Jan;
(83):e51185.
PMID: 24457629
Antifreeze proteins (AFPs) are expressed in a variety of cold-hardy organisms to prevent or slow internal ice growth. AFPs bind to specific planes of ice through their ice-binding surfaces. Fluorescence-based...