Patrick G Shaw
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Explore the profile of Patrick G Shaw including associated specialties, affiliations and a list of published articles.
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15
Citations
2066
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Recent Articles
1.
Li R, Liao G, Nirujogi R, Pinto S, Shaw P, Huang T, et al.
PLoS Pathog
. 2015 Dec;
11(12):e1005346.
PMID: 26714015
Epstein-Barr virus (EBV) is etiologically linked to infectious mononucleosis and several human cancers. EBV encodes a conserved protein kinase BGLF4 that plays a key role in the viral life cycle....
2.
Mitchell C, Getnet D, Kim M, Manda S, Kumar P, Huang T, et al.
BMC Syst Biol
. 2015 Nov;
9:75.
PMID: 26542228
Background: Cellular function and diversity are orchestrated by complex interactions of fundamental biomolecules including DNA, RNA and proteins. Technological advances in genomics, epigenomics, transcriptomics and proteomics have enabled massively parallel...
3.
Zhang X, Belkina N, Charles Jacob H, Maity T, Biswas R, Venugopalan A, et al.
Proteomics
. 2014 Nov;
15(2-3):340-55.
PMID: 25404012
Mutations in the epidermal growth factor receptor (EGFR) kinase domain occur in 10-30% of lung adenocarcinoma and are associated with tyrosine kinase inhibitor (TKI) sensitivity. We sought to identify the...
4.
Kim M, Pinto S, Getnet D, Nirujogi R, Manda S, Chaerkady R, et al.
Nature
. 2014 May;
509(7502):575-81.
PMID: 24870542
The availability of human genome sequence has transformed biomedical research over the past decade. However, an equivalent map for the human proteome with direct measurements of proteins and peptides does...
5.
Haeusler A, Donnelly C, Periz G, Simko E, Shaw P, Kim M, et al.
Nature
. 2014 Mar;
507(7491):195-200.
PMID: 24598541
A hexanucleotide repeat expansion (HRE), (GGGGCC)n, in C9orf72 is the most common genetic cause of the neurodegenerative diseases amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Here we identify a...
6.
Nanjappa V, Thomas J, Marimuthu A, Muthusamy B, Radhakrishnan A, Sharma R, et al.
Nucleic Acids Res
. 2013 Dec;
42(Database issue):D959-65.
PMID: 24304897
Plasma Proteome Database (PPD; http://www.plasmaproteomedatabase.org/) was initially described in the year 2005 as a part of Human Proteome Organization's (HUPO's) pilot initiative on Human Plasma Proteome Project. Since then, improvements...
7.
Shaw P, Chaerkady R, Wang T, Vasilatos S, Huang Y, Van Houten B, et al.
PLoS One
. 2013 Oct;
8(9):e76220.
PMID: 24086712
One of the most persistent hallmarks of cancer biology is the preference of tumor cells to derive energy through glycolysis as opposed to the more efficient process of oxidative phosphorylation...
8.
Huang Y, Shaw P, Davidson N
Methods Mol Biol
. 2011 Sep;
791:297-311.
PMID: 21913088
Lysine acetylation of histones is one of the major epigenetic regulators of chromatin conformation and gene expression. The dynamic nature of histone acetylation is determined by the counterbalancing activity of...
9.
Agyeman A, Chaerkady R, Shaw P, Davidson N, Visvanathan K, Pandey A, et al.
Breast Cancer Res Treat
. 2011 May;
132(1):175-87.
PMID: 21597922
Sulforaphane (SFN), an isothiocyanate found in cruciferous vegetables, is a potent inhibitor of experimental mammary carcinogenesis and may be an effective, safe chemopreventive agent for use in humans. SFN acts...
10.
Shaw P, Chaerkady R, Zhang Z, Davidson N, Pandey A
Anal Chem
. 2011 Apr;
83(10):3623-6.
PMID: 21466224
The availability and robustness of methods to analyze phosphorylated proteins has greatly expanded our knowledge of phosphorylation based cell signaling. A key ingredient to the success of these studies is...