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Patrick G Shaw

Explore the profile of Patrick G Shaw including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 2066
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Recent Articles
11.
Huang Y, Vasilatos S, Boric L, Shaw P, Davidson N
Breast Cancer Res Treat . 2011 Apr; 131(3):777-89. PMID: 21452019
Abnormal activities of histone lysine demethylases (KDMs) and lysine deacetylases (HDACs) are associated with aberrant gene expression in breast cancer development. However, the precise molecular mechanisms underlying the crosstalk between...
12.
Zhou Q, Chaerkady R, Shaw P, Kensler T, Pandey A, Davidson N
Proteomics . 2010 Jan; 10(5):1029-39. PMID: 20049865
Histone deacetylases (HDACs) play critical roles in silencing tumor suppressor genes. HDAC inhibitors reactivate tumor suppressor genes and inhibit tumor cell growth in vitro and in vivo, and several HDAC...
13.
Zhou Q, Shaw P, Davidson N
Endocr Relat Cancer . 2009 Feb; 16(2):319-23. PMID: 19208734
No abstract available.
14.
Zhou Q, Shaw P, Davidson N
Breast Cancer Res Treat . 2008 Aug; 117(2):443-51. PMID: 18683042
Estrogen receptor alpha (ER)-negative human breast cancer cells frequently overexpress epidermal growth factor receptor (EGFR) and respond poorly to endocrine therapies. Our previous studies demonstrate that histone deacetylation plays a...
15.
Fitzpatrick P, Bozinovski D, Heroux A, Shaw P, Valley M, Orville A
Biochemistry . 2007 Nov; 46(48):13800-8. PMID: 17994768
The flavoprotein nitroalkane oxidase (NAO) catalyzes the oxidation of primary and secondary nitroalkanes to the corresponding aldehydes and ketones. The enzyme is a homologue of acyl-CoA dehydrogenase. Asp402 in NAO...