Patrick G Bray
Overview
Explore the profile of Patrick G Bray including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
59
Citations
1349
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Rajoli R, Pertinez H, Arshad U, Box H, Tatham L, Curley P, et al.
Br J Clin Pharmacol
. 2020 Oct;
87(4):2078-2088.
PMID: 33085781
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a global pandemic and urgent treatment and prevention strategies are needed. Nitazoxanide, an anthelmintic drug, has been shown to...
2.
Rajoli R, Pertinez H, Arshad U, Box H, Tatham L, Curley P, et al.
medRxiv
. 2020 Jun;
PMID: 32511548
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared a global pandemic by the World Health Organisation and urgent treatment and prevention strategies are needed. Many clinical trials...
3.
Arshad U, Pertinez H, Box H, Tatham L, Rajoli R, Curley P, et al.
Clin Pharmacol Ther
. 2020 May;
108(4):775-790.
PMID: 32438446
There is a rapidly expanding literature on the in vitro antiviral activity of drugs that may be repurposed for therapy or chemoprophylaxis against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). However,...
4.
van Schalkwyk D, Saliba K, Biagini G, Bray P, Kirk K
PLoS One
. 2013 Mar;
8(3):e58933.
PMID: 23536836
The intraerythrocytic malaria parasite is susceptible to oxidative stress and this may play a role in the mechanism of action of some antimalarial agents. Here we show that exposure of...
5.
Patzewitz E, Salcedo-Sora J, Wong E, Sethia S, Stocks P, Maughan S, et al.
Antioxid Redox Signal
. 2012 Dec;
19(7):683-95.
PMID: 23256874
Aims: Chloroquine (CQ) kills Plasmodium falciparum by binding heme, preventing its detoxification to hemozoin in the digestive vacuole (DV) of the parasite. CQ resistance (CQR) is associated with mutations in...
6.
Salcedo-Sora J, Ochong E, Beveridge S, Johnson D, Nzila A, Biagini G, et al.
J Biol Chem
. 2011 Oct;
286(52):44659-68.
PMID: 21998306
Tetrahydrofolates are essential cofactors for DNA synthesis and methionine metabolism. Malaria parasites are capable both of synthesizing tetrahydrofolates and precursors de novo and of salvaging them from the environment. The...
7.
Berger O, Kaniti A, Van Ba C, Vial H, Ward S, Biagini G, et al.
ChemMedChem
. 2011 Sep;
6(11):2094-108.
PMID: 21905228
Four different series of triazole diamidines have been prepared by the Pinner method from the corresponding triazole dinitriles. Copper-catalyzed "click chemistry" was used for the synthesis of 1,4- and 4,5-substituted...
8.
Chaijaroenkul W, Ward S, Mungthin M, Johnson D, Owen A, Bray P, et al.
Malar J
. 2011 Feb;
10:42.
PMID: 21320353
Background: Plasmodium falciparum chloroquine resistance (CQR) transporter protein (PfCRT) is known to be the important key of CQR. Recent studies have definitively demonstrated a link between mutations in the gene...
9.
ONeill P, Amewu R, Nixon G, Bousejra ElGarah F, Mungthin M, Chadwick J, et al.
Angew Chem Int Ed Engl
. 2010 Jul;
49(33):5693-7.
PMID: 20629058
No abstract available.
10.
Henry R, Cobbold S, Allen R, Khan A, Hayward R, Lehane A, et al.
J Biol Chem
. 2010 Mar;
285(24):18615-26.
PMID: 20332090
The intraerythrocytic malaria parasite exerts tight control over its ionic composition. In this study, a combination of fluorescent ion indicators and (36)Cl(-) flux measurements was used to investigate the transport...