Patricia D A Lima
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Explore the profile of Patricia D A Lima including associated specialties, affiliations and a list of published articles.
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30
Citations
501
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Recent Articles
1.
Wu D, Jansen-van Vuuren R, Dasgupta A, Al-Qazazi R, Chen K, Martin A, et al.
Hypertension
. 2024 Aug;
81(10):2189-2201.
PMID: 39162036
Background: Drp1 (dynamin-related protein 1), a large GTPase, mediates the increased mitochondrial fission, which contributes to hyperproliferation of pulmonary artery smooth muscle cells in pulmonary arterial hypertension (PAH). We developed...
2.
Xiao C, Carbonel A, Lima P, Hendry A, Tsang B
Br J Nutr
. 2024 Jun;
:1-9.
PMID: 38826091
Polycystic ovary syndrome is associated with increased risks for certain metabolic disorders such as insulin resistance, non-alcoholic fatty liver disease and suppressed ovarian follicular development. This study aimed to examine...
3.
Al-Qazazi R, Emon I, Potus F, Martin A, Lima P, Vlasschaert C, et al.
medRxiv
. 2024 Jan;
PMID: 38234783
Background: Mutations are found in 10-20% of idiopathic PAH (IPAH) patients, but none are consistently identified in connective tissue disease-associated PAH (APAH), which accounts for ∼45% of PAH cases. mutations,...
4.
Vieira R, da Silva R, Sasso G, Franco P, Borges F, Lima P, et al.
Inflammation
. 2024 Jan;
47(3):1041-1052.
PMID: 38198110
Annexin A1 (AnxA1) is a glucocorticoid-inducible protein and an important endogenous modulator of inflammation. However, its effect in the endometrial microenvironment is poorly explained. This study aimed to evaluate the...
5.
Wu D, Jansen-van Vuuren R, Dasgupta A, Al-Qazazi R, Chen K, Martin A, et al.
bioRxiv
. 2024 Jan;
PMID: 38187628
Rationale: Dynamin-related protein 1 (Drp1), a large GTPase, mediates mitochondrial fission. Increased Drp1-mediated fission permits accelerated mitosis, contributing to hyperproliferation of pulmonary artery smooth muscle cells (PASMC), which characterizes pulmonary...
6.
Read A, Bentley R, Martin A, Mewburn J, Alizadeh E, Wu D, et al.
J Am Heart Assoc
. 2023 Jun;
12(13):e029131.
PMID: 37345832
Background As partial pressure of oxygen (pO) rises with the first breath, the ductus arteriosus (DA) constricts, diverting blood flow to the pulmonary circulation. The DA's O sensor resides within...
7.
Vanderkooi S, Zhao Y, Lima P, Kan F
J Assist Reprod Genet
. 2022 Aug;
39(10):2287-2301.
PMID: 35972586
Purpose: To investigate the effects of recombinant human oviduct-specific glycoprotein (rHuOVGP1) alone and in combination with progesterone (P4) on intracellular Ca concentration [Ca] and to investigate if rHuOVGP1 in combination...
8.
Al-Qazazi R, Lima P, Prisco S, Potus F, Dasgupta A, Chen K, et al.
Am J Respir Crit Care Med
. 2022 Jun;
206(5):608-624.
PMID: 35699679
Pulmonary arterial hypertension (PAH) often results in death from right ventricular failure (RVF). NLRP3 (nucleotide-binding domain, leucine-rich-containing family, pyrin domain-containing-3)-macrophage activation may promote RVF in PAH. Evaluating the contribution of...
9.
Bowman M, Casey L, Selvam S, Lima P, Rawley O, Hinds M, et al.
J Thromb Haemost
. 2022 Apr;
20(7):1599-1609.
PMID: 35466528
Background: von Willebrand factor (VWF) is synthesized by vascular endothelial cells and megakaryocytes. The VWF propeptide is critical for multimerization and acts as an intra-molecular chaperone for mature VWF in...
10.
Bentley R, Hindmarch C, Dunham-Snary K, Snetsinger B, Mewburn J, Thebaud A, et al.
Data Brief
. 2022 Jan;
40:107736.
PMID: 35005134
The Ductus Arteriosus (DA) is a fetal vessel that connects the aorta to the pulmonary artery ensuring that placental oxygenated blood is diverted from the lungs to the systemic circulation....