Patricia Casado
Overview
Explore the profile of Patricia Casado including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
3
Citations
17
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0
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Recent Articles
1.
MacLeod A, Coquelin K, Huertas L, Simeons F, Riley J, Casado P, et al.
Proc Natl Acad Sci U S A
. 2024 Feb;
121(7):e2315069121.
PMID: 38315851
A key step in drug discovery, common to many disease areas, is preclinical demonstration of efficacy in a mouse model of disease. However, this demonstration and its translation to the...
2.
Negatu D, Gonzalez Del Rio R, Cacho-Izquierdo M, Barros-Aguirre D, Lelievre J, Rullas J, et al.
Antimicrob Agents Chemother
. 2023 Jan;
67(2):e0145922.
PMID: 36688684
The combination of the β-lactam tebipenem and the β-lactamase inhibitor avibactam shows potent bactericidal activity against Mycobacterium abscessus . Here, we report that the combination of the respective oral prodrugs...
3.
Flipo M, Frita R, Bourotte M, Martinez-Martinez M, Boesche M, Boyle G, et al.
Sci Transl Med
. 2022 May;
14(643):eaaz6280.
PMID: 35507672
The sensitivity of , the pathogen that causes tuberculosis (TB), to antibiotic prodrugs is dependent on the efficacy of the activation process that transforms the prodrugs into their active antibacterial...