Martin Moune
Overview
Explore the profile of Martin Moune including associated specialties, affiliations and a list of published articles.
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7
Citations
91
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0
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Recent Articles
1.
Flipo M, Frita R, Bourotte M, Martinez-Martinez M, Boesche M, Boyle G, et al.
Sci Transl Med
. 2022 May;
14(643):eaaz6280.
PMID: 35507672
The sensitivity of , the pathogen that causes tuberculosis (TB), to antibiotic prodrugs is dependent on the efficacy of the activation process that transforms the prodrugs into their active antibacterial...
2.
Faion L, Djaout K, Frita R, Pintiala C, Cantrelle F, Moune M, et al.
Eur J Med Chem
. 2020 Jun;
200:112440.
PMID: 32505086
Mycobacterium tuberculosis (M.tb), the etiologic agent of tuberculosis, remains the leading cause of death from a single infectious agent worldwide. The emergence of drug-resistant M.tb strains stresses the need for...
3.
Villemagne B, Machelart A, Tran N, Flipo M, Moune M, Leroux F, et al.
ACS Infect Dis
. 2020 Feb;
6(3):366-378.
PMID: 32011115
Killing more than one million people each year, tuberculosis remains the leading cause of death from a single infectious agent. The growing threat of multidrug-resistant strains of stresses the need...
4.
Prevet H, Moune M, Tanina A, Kemmer C, Herledan A, Frita R, et al.
Eur J Med Chem
. 2019 Feb;
167:426-438.
PMID: 30784877
Tuberculosis (TB) caused by the pathogen Mycobacterium tuberculosis, represents one of the most challenging threat to public health worldwide, and with the increasing resistance to approved TB drugs, it is...
5.
Tanina A, Wohlkonig A, Soror S, Flipo M, Villemagne B, Prevet H, et al.
Biochim Biophys Acta Proteins Proteom
. 2018 Dec;
1867(3):248-258.
PMID: 30553830
The Mycobacterium tuberculosis EthR is a member of the TetR family of repressors, controlling the expression of EthA, a mono-oxygenase responsible for the bioactivation of the prodrug ethionamide. This protein...
6.
Wohlkonig A, Remaut H, Moune M, Tanina A, Meyer F, Desroses M, et al.
Biochem Biophys Res Commun
. 2017 Apr;
487(2):403-408.
PMID: 28416386
Inhibition of transcriptional regulators of bacterial pathogens with the aim of reprogramming their metabolism to modify their antibiotic susceptibility constitutes a promising therapeutic strategy. One example is the bio-activation of...
7.
Blondiaux N, Moune M, Desroses M, Frita R, Flipo M, Mathys V, et al.
Science
. 2017 Mar;
355(6330):1206-1211.
PMID: 28302858
Antibiotic resistance is one of the biggest threats to human health globally. Alarmingly, multidrug-resistant and extensively drug-resistant have now spread worldwide. Some key antituberculosis antibiotics are prodrugs, for which resistance...