Pascale Lesage
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Explore the profile of Pascale Lesage including associated specialties, affiliations and a list of published articles.
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30
Citations
514
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Recent Articles
11.
Asif-Laidin A, Conesa C, Bonnet A, Grison C, Adhya I, Menouni R, et al.
EMBO J
. 2020 Jul;
39(17):e104337.
PMID: 32677087
Integration of transposable elements into the genome is mutagenic. Mechanisms targeting integrations into relatively safe locations, hence minimizing deleterious consequences for cell fitness, have emerged during evolution. In budding yeast,...
12.
Beauclair G, Tchalikian-Cosson A, Bridier-Nahmias A, Zamborlini A, Lesage P, Saib A
Virologie (Montrouge)
. 2019 Dec;
16(2):73-84.
PMID: 31881589
Integration into the genome of the host cell is an obligatory step in the replication of retroelements. This feature accounts for the fact that these elements are both potential mutagens...
13.
Barkova A, Asif-Laidin A, Lesage P
Methods Enzymol
. 2018 Dec;
612:197-223.
PMID: 30502942
Transposable elements (TEs) are present in virtually all organisms. TE integration into genomes contributes to their structure and evolution, but can also be harmful in some cases. Deciphering where and...
14.
Lesage P, Betermier M, Bridier-Nahmias A, Chandler M, Chambeyron S, Cristofari G, et al.
Mob DNA
. 2018 Jul;
7:19.
PMID: 30044887
The third international conference on Transposable Elements (ICTE) was held 16-19 April 2016 in Saint Malo, France. Organized by the French Transposition Community (Research group of the CNRS: "Mobile genetic...
15.
Paris J, Tobaly-Tapiero J, Giron M, Burlaud-Gaillard J, Buseyne F, Roingeard P, et al.
Retrovirology
. 2018 Jul;
15(1):48.
PMID: 29996845
Background: Nuclear localization of Gag is a property shared by many retroviruses and retrotransposons. The importance of this stage for retroviral replication is still unknown, but studies on the Rous...
16.
de Mendoza A, Bonnet A, Vargas-Landin D, Ji N, Li H, Yang F, et al.
Nat Commun
. 2018 May;
9(1):1811.
PMID: 29717194
The original version of this Article contained an error in the spelling of the author Hongfei Li, which was incorrectly given as Fei Hong. This has now been corrected in...
17.
de Mendoza A, Bonnet A, Vargas-Landin D, Ji N, Li H, Yang F, et al.
Nat Commun
. 2018 Apr;
9(1):1341.
PMID: 29632298
Transposable elements are in a constant arms race with the silencing mechanisms of their host genomes. One silencing mechanism commonly used by many eukaryotes is dependent on cytosine methylation, a...
18.
Luciano P, Jeon J, El-Kaoutari A, Challal D, Bonnet A, Barucco M, et al.
Cell Discov
. 2017 Oct;
3:17040.
PMID: 29071121
The Set1 family of histone H3 lysine 4 (H3K4) methyltransferases is highly conserved from yeast to human. Here we show that the Set1 complex (Set1C) directly binds RNA through the...
19.
Sultana T, Zamborlini A, Cristofari G, Lesage P
Nat Rev Genet
. 2017 Mar;
18(5):292-308.
PMID: 28286338
Transposable elements and retroviruses are found in most genomes, can be pathogenic and are widely used as gene-delivery and functional genomics tools. Exploring whether these genetic elements target specific genomic...
20.
Buseyne F, Gessain A, Soares M, Santos A, Materniak-Kornas M, Lesage P, et al.
Viruses
. 2016 Nov;
8(11).
PMID: 27886074
The Eleventh International Foamy Virus Conference took place on 9-10 June 2016 at the Institut Pasteur, Paris, France. The meeting reviewed progress on foamy virus (FV) research, as well as...