Pascal Schneider
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Explore the profile of Pascal Schneider including associated specialties, affiliations and a list of published articles.
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191
Citations
8447
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Recent Articles
1.
Ahmed M, Kakunuri T, Peris L, Meffre D, Yilmaz E, Grewing L, et al.
Brain Commun
. 2025 Feb;
7(1):fcae473.
PMID: 39926615
Lesions in the CNS are frequently associated to a detrimental inflammatory reaction. In autoimmune neurodegenerative diseases, a proliferation-inducing ligand (APRIL) produced by CNS-infiltrating inflammatory cells binds to chondroitin sulphate proteoglycans...
2.
Schneider P, Fandrey J, Leu T
Am J Physiol Cell Physiol
. 2024 Dec;
328(2):C381-C386.
PMID: 39714449
Over the past few decades, the primary cilium, an inconspicuous cell organelle, has increasingly become the focus of current research. The primary cilium is a microtubule-based, nonmotile, antenna-like structure that...
3.
Tong D, He Y, Haile S, Lee Z, Le L, Emery J, et al.
Eur J Immunol
. 2024 Dec;
55(2):e202451355.
PMID: 39686777
Helicobacter infection is a key cause of gastric B cell mucosa-associated lymphoid tissue (MALT) lymphoma. This study examined the role of B cell-activating factor (BAFF), a major driver of B...
4.
Petchey M, Schneider P, Harwood L
ChemMedChem
. 2024 Nov;
20(5):e202400628.
PMID: 39540701
The success of new therapeutic modalities relies on advancements in synthetic chemistry to produce compounds for evaluation throughout the drug discovery process. The use of non-canonical amino acids (ncAAs) allows...
5.
Felten R, Foray A, Schneider P, Marquet C, Pecquet C, Monneaux F, et al.
RMD Open
. 2024 Aug;
10(3).
PMID: 39209370
Introduction: The therapeutic interest of targeting B-cell activating factor (BAFF) in Sjögren's disease (SjD) can be suspected from the results of two phase II clinical trials but has not been...
6.
Eslami M, Schuepbach-Mallepell S, Diana D, Willen L, Kowalczyk-Quintas C, Desponds C, et al.
Proc Natl Acad Sci U S A
. 2024 Jul;
121(29):e2404309121.
PMID: 38990948
Antibody-producing plasma cells fuel humoral immune responses. They also contribute to autoimmune diseases such as systemic lupus erythematosus or IgA nephropathy. Interleukin-6 and the tumor necrosis factor (TNF) family ligands...
7.
Ullah M, Garcillan B, Whitlock E, Figgett W, Infantino S, Eslami M, et al.
Front Immunol
. 2024 Mar;
15:1345515.
PMID: 38469292
Background: Chronic Lymphocytic Leukemia (CLL) is characterized by the expansion of CD19 CD5 B cells but its origin remains debated. Mutated CLL may originate from post-germinal center B cells and...
8.
Reinartz S, Weiss C, Heppelmann M, Hewicker-Trautwein M, Hellige M, Willen L, et al.
Genes (Basel)
. 2024 Jan;
15(1).
PMID: 38275590
Mutations within the gene have been associated with congenital hypotrichosis and anodontia (HAD/XHED) in humans, mice, dogs and cattle. We identified a three-generation family of Fleckvieh cattle with male calves...
9.
Non-apoptotic FAS signaling controls mTOR activation and extrafollicular maturation in human B cells
Staniek J, Kalina T, Andrieux G, Boerries M, Janowska I, Fuentes M, et al.
Sci Immunol
. 2024 Jan;
9(91):eadj5948.
PMID: 38215192
Defective FAS (CD95/Apo-1/TNFRSF6) signaling causes autoimmune lymphoproliferative syndrome (ALPS). Hypergammaglobulinemia is a common feature in ALPS with mutations (ALPS-FAS), but paradoxically, fewer conventional memory cells differentiate from FAS-expressing germinal center...
10.
Haase M, David B, Paschold B, Classen T, Schneider P, Pozhydaieva N, et al.
ACS Catal
. 2024 Jan;
14(1):227-236.
PMID: 38205025
Even though pyrroloindoles are widely present in natural products with different kinds of biological activities, their selective synthesis remains challenging with existing tools in organic chemistry, and there is furthermore...