Andrew F G Quest
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Explore the profile of Andrew F G Quest including associated specialties, affiliations and a list of published articles.
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131
Citations
3152
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Recent Articles
1.
Pena-Oyarzun D, Quest A, Lobos-Gonzalez L, Maturana-Ramirez A, Reyes M
Neoplasia
. 2024 Dec;
59:101097.
PMID: 39616893
Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer, which is usually preceded by a potentially malignant disorder histologically diagnosed as dysplasia. We and others have...
2.
Cifuentes M, Verdejo H, Castro P, Corvalan A, Ferreccio C, Quest A, et al.
Physiology (Bethesda)
. 2024 Jul;
40(1).
PMID: 39078396
Inflammation is an important physiological response of the organism to restore homeostasis upon pathogenic or damaging stimuli. However, the persistence of the harmful trigger or a deficient resolution of the...
3.
Simon L, Torres K, Contreras P, Diaz-Valdivia N, Leyton L, Quest A
Biomed Pharmacother
. 2024 Jun;
176:116841.
PMID: 38834004
Metastasis is the leading cause of cancer-related deaths, making the development of novel, more effective therapies imperative to alleviate patient suffering. Metabolic switching is a hallmark of cancer cells that...
4.
Yanez L, Soto C, Tapia H, Pacheco M, Tapia J, Osses G, et al.
Int J Mol Sci
. 2024 Apr;
25(7).
PMID: 38612423
Periodontitis, characterized by persistent inflammation in the periodontium, is intricately connected to systemic diseases, including oral cancer. Bacteria, such as and , play a pivotal role in periodontitis development because...
5.
Lobos-Gonzalez L, Orostica L, Diaz-Valdivia N, Rojas-Celis V, Campos A, Duran-Jara E, et al.
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38069269
Caveolin-1 (CAV1) is a membrane-bound protein that suppresses tumor development yet also promotes metastasis. E-cadherin is important in CAV1-dependent tumor suppression and prevents CAV1-enhanced lung metastasis. Here, we used murine...
6.
Paredes F, Navarro-Marquez M, Quiroga C, Jimenez-Gallegos D, Yeligar S, Parra V, et al.
Free Radic Biol Med
. 2023 Dec;
211:24-34.
PMID: 38043868
The intricate relationship between calcium (Ca) homeostasis and mitochondrial function is crucial for cellular metabolic adaptation in tumor cells. Ca-initiated signaling maintains mitochondrial respiratory capacity and ATP synthesis, influencing critical...
7.
Hidalgo A, Bravo D, Soto C, Maturana G, Cordero-Machuca J, Zuniga-Lopez M, et al.
Antioxidants (Basel)
. 2023 Oct;
12(10).
PMID: 37891945
The bacterium () represents a major risk factor associated with the development of gastric cancer. The anti-oxidant curcumin has been ascribed many benefits to human health, including bactericidal effects. However,...
8.
Pena-Oyarzun D, Flores T, Torres V, Quest A, Lobos-Gonzalez L, Kretschmar C, et al.
Clin Cancer Res
. 2023 Oct;
30(1):209-223.
PMID: 37812478
Purpose: Oral squamous cell carcinoma (OSCC) is commonly preceded by potentially malignant lesions, referred to as oral dysplasia. We recently reported that oral dysplasia is associated with aberrant activation of...
9.
Simon L, Arazo-Rusindo M, Quest A, Mariotti-Celis M
Antioxidants (Basel)
. 2023 Sep;
12(9).
PMID: 37760037
Mitochondrial dysfunction is an interesting therapeutic target to help reduce cancer deaths, and the use of bioactive compounds has emerged as a novel and safe approach to solve this problem....
10.
Palacios E, Lobos-Gonzalez L, Guerrero S, Kogan M, Shao B, Heinecke J, et al.
J Neuroinflammation
. 2023 Mar;
20(1):66.
PMID: 36895046
Background: Helicobacter pylori (Hp) infects the stomach of 50% of the world's population. Importantly, chronic infection by this bacterium correlates with the appearance of several extra-gastric pathologies, including neurodegenerative diseases....