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Part Peterson

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Articles 138
Citations 7598
Followers 0
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Recent Articles
1.
Giraud M, Peterson P
Adv Exp Med Biol . 2025 Mar; 1471:199-221. PMID: 40067588
It has been more than 20 years since the AIRE gene was discovered. The mutations in the AIRE gene cause a rare and life-threatening autoimmune disease with severe manifestations against...
2.
Lepland A, Peranzoni E, Haljasorg U, Asciutto E, Crespi-Amer M, Modesti L, et al.
Adv Sci (Weinh) . 2025 Jan; 12(10):e2410288. PMID: 39840532
In triple-negative breast cancer (TNBC), pro-tumoral macrophages promote metastasis and suppress the immune response. To target these cells, a previously identified CD206 (mannose receptor)-binding peptide, mUNO was engineered to enhance...
3.
Plaas M, Brazovskaja A, Kisand K, Tserel L, Peterson P
Clin Case Rep . 2024 Dec; 12(12):e9692. PMID: 39655286
We identified two CRSwNP patients who had previously failed treatment with an anti-IL-4/IL-13 antibody (dupilumab). Based on their clinical characteristics and blood cytokine levels, we considered them mixed Type II/Type...
4.
Filippov I, Schauser L, Peterson P
NPJ Aging . 2024 Nov; 10(1):59. PMID: 39613786
Recent advances in single-cell technologies have facilitated studies on age-related alterations in the immune system. However, previous studies have often employed different marker genes to annotate immune cell populations, making...
5.
Filippov I, Philip C, Schauser L, Peterson P
BMC Genomics . 2024 Nov; 25(1):1069. PMID: 39528918
Background: Single-cell RNA sequencing experiments commonly use 10x Genomics (10x) kits due to their high-throughput capacity and standardized protocols. Recently, Parse Biosciences (Parse) introduced an alternative technology that uses multiple...
6.
Daga N, Servaas N, Kisand K, Moonen D, Arnold C, Reyes-Palomares A, et al.
Cell Rep . 2024 Oct; 43(10):114810. PMID: 39388354
CD4 T cells play a crucial role in adaptive immune responses and have been implicated in the pathogenesis of autoimmune diseases (ADs). Despite numerous studies, the molecular mechanisms underlying T ...
7.
Hetemaki I, Heikkila N, Peterson P, Kekalainen E, Willcox N, Anette S B W, et al.
APMIS . 2024 Aug; 132(11):881-887. PMID: 39113427
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is an inborn error of immunity affecting both multiple endocrine organs and susceptibility to candidiasis, each with an autoimmune basis. Recently, high titer neutralizing anti-type I...
8.
Edner N, Houghton L, Ntavli E, Rees-Spear C, Petersone L, Wang C, et al.
Front Immunol . 2024 Jun; 15:1395684. PMID: 38868776
Circulating follicular helper T cells (cTfh) can show phenotypic alterations in disease settings, including in the context of tissue-damaging autoimmune or anti-viral responses. Using severe COVID-19 as a paradigm of...
9.
Sjogren T, Islam S, Filippov I, Jebrzycka A, Sulen A, Breivik L, et al.
iScience . 2024 Apr; 27(4):109610. PMID: 38632993
Immune tolerance fails in autoimmune polyendocrine syndrome type 1 (APS-1) because of mutations. We have used single cell transcriptomics to characterize regulatory T cells (Tregs) sorted directly from blood and...
10.
Peterson P
Adv Exp Med Biol . 2024 Mar; 1444:3-18. PMID: 38467969
Autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a monogenic inborn error of autoimmunity that is caused by damaging germline variants in the AIRE gene and clinically manifests with multiple autoimmune diseases in patients....