Paloma B Liton
Overview
Explore the profile of Paloma B Liton including associated specialties, affiliations and a list of published articles.
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49
Citations
7167
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Recent Articles
1.
Shim M, Sim E, Betsch K, Desikan V, Su C, Pastor-Valverde D, et al.
Cell Mol Life Sci
. 2025 Feb;
82(1):82.
PMID: 39985671
Elevated intraocular pressure (IOP) is the primary risk factor for glaucoma, a leading cause of irreversible blindness worldwide. IOP homeostasis is maintained through a balance between aqueous humor production and...
2.
Su C, Desikan V, Betsch K, Shim M, Keller K, Liton P
Invest Ophthalmol Vis Sci
. 2025 Jan;
66(1):43.
PMID: 39820277
Purpose: To study the roles of tubulin acetylation and cyclic mechanical stretch (CMS) in trabecular meshwork (TM) cells and their impact on outflow pathway physiology and pathology. Methods: Primary TM...
3.
Dixon A, Shim M, Nettesheim A, Coyne A, Su C, Gong H, et al.
Autophagy Rep
. 2024 Dec;
3(1).
PMID: 39726939
Glaucoma encompasses a spectrum of disorders characterized by the chronic degeneration of retinal ganglion cell (RGC) axons and the progressive loss of RGCs, resulting in visual impairment. In this study,...
4.
Shim M, Liton P
Methods Mol Biol
. 2024 Oct;
2858:77-86.
PMID: 39433668
The role of shear stress in regulating aqueous humor (AH) outflow and intraocular pressure (IOP) in the trabecular meshwork (TM) and Schlemm's canal (SC) of the eye is an emerging...
5.
Prosseda P, Dannewitz Prosseda S, Tran M, Liton P, Sun Y
Curr Top Dev Biol
. 2023 Dec;
155:1-37.
PMID: 38043949
Autophagy is a fundamental catabolic process whereby excessive or damaged cytoplasmic components are degraded through lysosomes to maintain cellular homeostasis. Studies of mTOR signaling have revealed that mTOR controls biomass...
6.
Shim M, Dixon A, Nettesheim A, Perkumas K, Stamer W, Sun Y, et al.
Autophagy Rep
. 2023 Aug;
2(1).
PMID: 37637387
The Schlemm's canal (SC) is a circular, lymphatic-like vessel located at the limbus of the eye that participates in the regulation of aqueous humor drainage to control intraocular pressure (IOP)....
7.
Dixon A, Shim M, Nettesheim A, Coyne A, Su C, Gong H, et al.
Cell Death Dis
. 2023 Aug;
14(8):554.
PMID: 37620383
Glaucoma is a group of diseases that leads to chronic degeneration of retinal ganglion cell (RGC) axons and progressive loss of RGCs, resulting in vision loss. While aging and elevated...
8.
Liton P, Boesze-Battaglia K, Boulton M, Boya P, Ferguson T, Ganley I, et al.
Autophagy Rep
. 2023 Apr;
2(1).
PMID: 37034386
Autophagy is a catabolic self-degradative pathway that promotes the degradation and recycling of intracellular material through the lysosomal compartment. Although first believed to function in conditions of nutritional stress, autophagy...
9.
Shim M, Liton P
Prog Retin Eye Res
. 2022 Apr;
90:101064.
PMID: 35370083
During the last few years, the autophagy lysosomal system is emerging as a central cellular pathway with roles in survival, acting as a housekeeper and stress response mechanism. Studies by...
10.
Shyam R, Ogando D, Choi M, Liton P, Bonanno J
Invest Ophthalmol Vis Sci
. 2021 Sep;
62(12):15.
PMID: 34533563
Purpose: The Slc4a11 knock out (KO) mouse model recapitulates the human disease phenotype associated with congenital hereditary endothelial dystrophy (CHED). Increased mitochondrial reactive oxygen species (ROS) in the Slc4a11 KO...