Padmaja Mehta-Dsouza
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Explore the profile of Padmaja Mehta-Dsouza including associated specialties, affiliations and a list of published articles.
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23
Citations
312
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Recent Articles
1.
Griffin T, Komaravolu R, Lopes E, Mehta-Dsouza P, Conner T, Kovats T, et al.
Sci Rep
. 2025 Jan;
15(1):2428.
PMID: 39827311
We hypothesized that daily exercise promotes joint health by upregulating anti-inflammatory mediators via adaptive molecular and metabolic changes in the infrapatellar fat pad (IFP). We tested this hypothesis by conducting...
2.
Griffin T, Lopes E, Cortassa D, Batushansky A, Jeffries M, Makosa D, et al.
Biol Sex Differ
. 2024 Dec;
15(1):103.
PMID: 39639386
Background: Women have a higher risk of developing osteoarthritis (OA) than men, including with obesity. To better understand this disparity, we investigated sex differences in metabolic and inflammatory factors associated...
3.
Komaravolu R, Mehta-Dsouza P, Conner T, Allen M, Lumry J, Batushansky A, et al.
Osteoarthritis Cartilage
. 2024 Mar;
32(9):1097-1112.
PMID: 38527663
Objective: Metabolic processes are intricately linked to the resolution of innate inflammation and tissue repair, two critical steps for treating post-traumatic osteoarthritis (PTOA). Based on lipolytic and immunoregulatory actions of...
4.
South S, Marlin M, Mehta-Dsouza P, Stephens T, Conner T, Burt K, et al.
Osteoarthr Cartil Open
. 2023 Dec;
5(4):100416.
PMID: 38107076
Objective: To develop an imaging mass cytometry method for identifying complex cell phenotypes, inter-cellular interactions, and population changes in the synovium and infrapatellar fat pad (IFP) of the mouse knee...
5.
Zhu S, Donovan E, Makosa D, Mehta-Dsouza P, Jopkiewicz A, Batushansky A, et al.
J Bone Miner Res
. 2022 Oct;
37(12):2531-2547.
PMID: 36214465
Understanding how obesity-induced metabolic stress contributes to synovial joint tissue damage is difficult because of the complex role of metabolism in joint development, maintenance, and repair. Chondrocyte mitochondrial dysfunction is...
6.
Mehta-Dsouza P
Methods Mol Biol
. 2022 Mar;
2442:125-135.
PMID: 35320523
Surface plasmon resonance (SPR) instruments, like the BIAcore 3000, are useful for studying the binding between macromolecules in real time. The high sensitivity and low sample consumption in the Biacore...
7.
Lu Y, Mehta-Dsouza P, Biswas I, Villoutreix B, Wang X, Ding Q, et al.
Haematologica
. 2019 Aug;
105(6):1712-1722.
PMID: 31399531
Activated protein C exerts its anticoagulant activity by protein S-dependent inactivation of factors Va and VIIIa by limited proteolysis. We identified a venous thrombosis patient who has plasma protein C...
8.
Mehta-Dsouza P
Methods Mol Biol
. 2018 Aug;
1853:115-119.
PMID: 30097936
Pro-Q Emerald 300 glycoprotein stain generates a bright-green fluorescent signal upon reacting with periodic acid-oxidized carbohydrate groups on proteins. With this dye it is possible to detect proteins directly in...
9.
Biswas I, Panicker S, Cai X, Mehta-Dsouza P, Rezaie A
Arterioscler Thromb Vasc Biol
. 2018 Jun;
38(8):1868-1877.
PMID: 29930000
Objective- Inorganic polyphosphate (polyP) is known to modulate coagulation, inflammation, and metabolic pathways. It also amplifies inflammatory responses of HMGB1 (high mobility group box 1) in endothelial cells. The objective...
10.
Panicker S, Mehta-Dsouza P, Zhang N, Klopocki A, Shao B, McEver R
Blood
. 2017 May;
130(2):181-191.
PMID: 28515093
Leukocyte adhesion to P-selectin on activated platelets and endothelial cells induces shedding of the P-selectin ectodomain into the circulation. Plasma soluble P-selectin (sP-selectin) is elevated threefold to fourfold in patients...