Pad Chivukula
Overview
Explore the profile of Pad Chivukula including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
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Articles
16
Citations
376
Followers
0
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Recent Articles
1.
Sawamura M, Tachikawa K, Hikawa R, Akiyama H, Kaji S, Yasuda K, et al.
Mol Ther Nucleic Acids
. 2024 Dec;
35(4):102380.
PMID: 39640012
Despite the wide range of applications of mRNA therapies, major difficulties exist in the efficient delivery of mRNA into oligodendrocytes, a type of glial cell in the brain. Commonly used...
2.
Garcia D, Pierre A, Quirino L, Acharya G, Vasudevan A, Pei Y, et al.
Mol Ther
. 2024 Nov;
33(1):90-103.
PMID: 39563033
Lipoprotein(a), or Lp(a), is encoded by the LPA gene and is a causal genetic risk factor for cardiovascular disease. Individuals with high Lp(a) are at risk for cardiovascular morbidity and...
3.
Oda Y, Kumagai Y, Kanai M, Iwama Y, Okura I, Minamida T, et al.
Lancet Infect Dis
. 2024 Oct;
24(12):e729-e731.
PMID: 39389075
No abstract available.
4.
H N, Hughes S, Ta V, Phan L, d Q, Nguyn T, et al.
Nat Commun
. 2024 May;
15(1):4081.
PMID: 38744844
Combination of waning immunity and lower effectiveness against new SARS-CoV-2 variants of approved COVID-19 vaccines necessitates new vaccines. We evaluated two doses, 28 days apart, of ARCT-154, a self-amplifying mRNA...
5.
Persistence of immune responses of a self-amplifying RNA COVID-19 vaccine (ARCT-154) versus BNT162b2
Oda Y, Kumagai Y, Kanai M, Iwama Y, Okura I, Minamida T, et al.
Lancet Infect Dis
. 2024 Feb;
24(4):341-343.
PMID: 38310906
No abstract available.
6.
Albers S, Allen E, Bharti N, Davyt M, Joshi D, Perez-Garcia C, et al.
Nature
. 2023 May;
618(7966):842-848.
PMID: 37258671
Nonsense mutations are the underlying cause of approximately 11% of all inherited genetic diseases. Nonsense mutations convert a sense codon that is decoded by tRNA into a premature termination codon...
7.
Low J, de Alwis R, Chen S, Kalimuddin S, Leong Y, Mah T, et al.
NPJ Vaccines
. 2022 Dec;
7(1):161.
PMID: 36513697
Coronavirus disease-19 (Covid-19) pandemic have demonstrated the importantance of vaccines in disease prevention. Self-amplifying mRNA vaccines could be another option for disease prevention if demonstrated to be safe and immunogenic....
8.
Ong E, Yee J, Ooi J, Syenina A, de Alwis R, Chen S, et al.
NPJ Vaccines
. 2022 Nov;
7(1):154.
PMID: 36443317
Remarkable potency has been demonstrated for mRNA vaccines in reducing the global burden of the ongoing COVID-19 pandemic. An alternative form of the mRNA vaccine is the self-amplifying mRNA (sa-mRNA)...
9.
Milbank E, Diaz-Trelles R, Dragano N, Latorre J, Mukthavaram R, Mayneris-Perxachs J, et al.
Pharmacol Res
. 2022 Nov;
187:106562.
PMID: 36410673
Lipopolysaccharide binding protein (LBP) knockout mice models are protected against the deleterious effects of major acute inflammation but its possible physiological role has been less well studied. We aimed to...
10.
Latorre J, Diaz-Trelles R, Comas F, Gavalda-Navarro A, Milbank E, Dragano N, et al.
Mol Ther Nucleic Acids
. 2022 Sep;
29:599-613.
PMID: 36090751
Circulating lipopolysaccharide-binding protein (LBP) is increased in individuals with liver steatosis. We aimed to evaluate the possible impact of liver LBP downregulation using lipid nanoparticle-containing chemically modified LBP small interfering...