P M van Endert
Overview
Explore the profile of P M van Endert including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
789
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Recent Articles
1.
Banga J, Moore J, Duhindan N, Madec A, van Endert P, Orgiazzi J, et al.
Clin Exp Immunol
. 2003 Dec;
135(1):74-84.
PMID: 14678267
We used a GAD65-specific human B-T cell line cognate system in vitro to investigate the modulation of GAD65 presentation by autoantibody, assessed in a proliferation assay. Generally, if the T...
2.
Cohen W, Bianco A, Connan F, Camoin L, Dalod M, Lauvau G, et al.
J Virol
. 2002 Sep;
76(20):10219-25.
PMID: 12239297
Cytotoxic T-lymphocyte (CTL) responses directed to different human immunodeficiency virus (HIV) epitopes vary in their protective efficacy. In particular, HIV-infected cells are much more sensitive to lysis by anti-Gag/p17(77-85)/HLA-A2 than...
3.
van Endert P
Biologicals
. 2002 Feb;
29(3-4):285-8.
PMID: 11851329
Synthetic peptides are safe and relatively cheap vaccine components. However, the efficiency of peptide vaccines is limited by peptide interaction with non-professional antigen-presenting cells, which may hamper induction of productive...
4.
Saveanu L, van Endert P
Adv Exp Med Biol
. 2002 Jan;
495:79-82.
PMID: 11774612
No abstract available.
5.
Fruci D, Niedermann G, Butler R, van Endert P
Immunity
. 2001 Sep;
15(3):467-76.
PMID: 11567636
MHC class I ligands are produced mainly by proteasomal proteolysis, in conjunction with an unknown extent of trimming by peptidases. Trimming of precursor peptides in the endoplasmic reticulum, a process...
6.
Saveanu L, Daniel S, van Endert P
J Biol Chem
. 2001 Apr;
276(25):22107-13.
PMID: 11290739
The transporters associated with antigen processing (TAP1/TAP2) provide peptides to MHC class I molecules in the endoplasmic reticulum. Like other ATP-binding cassette proteins, TAP uses ATP hydrolysis to power transport....
7.
De Oliveira D, Otto H, Papandreou N, Stern L, Cohen H, Boehm B, et al.
Mol Immunol
. 2001 Mar;
37(14):813-25.
PMID: 11257303
Specific and major histocompatibility complex (MHC)-restricted T-cell recognition of antigenic peptides is based on interactions of the T-cell receptor (TCR) with the MHC alpha helices and solvent exposed peptide residues...
8.
van Endert P, Lauvau G, Maier R, Meyerhans A, Mann D, Eichmann K, et al.
J Exp Med
. 2000 Jan;
191(2):239-52.
PMID: 10637269
Although a pivotal role of proteasomes in the proteolytic generation of epitopes for major histocompatibility complex (MHC) class I presentation is undisputed, their precise function is currently the subject of...
9.
Lauvau G, Kakimi K, Niedermann G, Ostankovitch M, Yotnda P, Firat H, et al.
J Exp Med
. 1999 Nov;
190(9):1227-40.
PMID: 10544195
Antigen presentation by major histocompatibility complex (MHC) class I molecules requires peptide supply by the transporters associated with antigen processing (TAPs), which select substrates in a species- and, in the...
10.
Lauvau G, Gubler B, Cohen H, Daniel S, Caillat-Zucman S, van Endert P
J Biol Chem
. 1999 Oct;
274(44):31349-58.
PMID: 10531335
Assembly of HLA class I-peptide complexes is assisted by multiple proteins that associate with HLA molecules in loading complexes. These include the housekeeping chaperones calnexin and calreticulin and two essential...