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P M Murphy

Explore the profile of P M Murphy including associated specialties, affiliations and a list of published articles. Areas
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Articles 149
Citations 7639
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Carevic M, Oz H, Fuchs K, Laval J, Schroth C, Frey N, et al.
J Innate Immun . 2016 Mar; 8(4):362-73. PMID: 26950764
Pseudomonas aeruginosa is a key opportunistic pathogen causing disease in cystic fibrosis (CF) and other lung diseases such as chronic obstructive pulmonary disease (COPD). However, the pulmonary host defense mechanisms...
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Alexander S, Benson H, Faccenda E, Pawson A, Sharman J, McGrath J, et al.
Br J Pharmacol . 2014 Feb; 170(8):1449-58. PMID: 24528237
The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of...
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Murphy P, Moore E, Flanagan D
Diabetes Res Clin Pract . 2014 Jan; 103(3):426-9. PMID: 24462281
Aims: Optimising glycaemic control for insulin requiring individuals during enteral feeding is important but difficult. We compare 3 insulin regimens with the aim of improving glucose control and reducing hypoglycaemia....
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Rosenberg A, Roivainen M, Hovi T, Liu Q, Murphy P
J Med Virol . 2013 Sep; 85(12):2139-40. PMID: 24037958
CCR5, a leukocyte chemoattractant receptor for chemokines CCL3, CCL4, and CCL5, promotes innate and adaptive immune responses by mediating leukocyte trafficking within lymph nodes and to peripheral tissues and is...
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Murphy P
Curr Protoc Neurosci . 2008 Apr; Chapter 4:Unit 4.20. PMID: 18428482
Many G protein-coupled receptors of interest to neuroscientists induce transient increases in [Ca(2+)](i), which can be used as a convenient measure of receptor activation in a variety of applications. This...
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Murphy P, Modi P, Rahamim J, Wheatley T, Lewis S
Ann R Coll Surg Engl . 2006 Jul; 88(4):358-62. PMID: 16834854
Introduction: Patients with oesophageal carcinoma are at high risk of malnutrition. The aim of this study was to assess current practice for the nutritional management of patients following surgery for...
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Murphy P, Stack D, Kinirons B, Laffey J
Anesth Analg . 2003 Nov; 97(6):1709-1715. PMID: 14633547
Unlabelled: Intrathecal (IT) morphine provides excellent postoperative analgesia but may result in many side effects, including postoperative nausea and vomiting, pruritus, and respiratory depression, particularly at larger doses. Older patients...
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Liang T, Gao J, Fatemi O, Lavigne M, Leto T, Murphy P
J Immunol . 2001 Nov; 167(11):6609-14. PMID: 11714831
Spinorphin is an endogenous heptapeptide (leucylvalylvalyltyrosylprolyltryptophylthreonine), first isolated from bovine spinal cord, whose sequence matches a conserved region of beta-hemoglobin. Also referred to as LVV-hemorphin-4 and a member of the...
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Sahagun-Ruiz A, Colla J, Juhn J, Gao J, Murphy P, McDermott D
Genes Immun . 2001 Oct; 2(6):335-42. PMID: 11607790
N-formylpeptides are phagocyte chemoattractants that act by binding to two structurally related receptors, FPR (formylpeptide receptor) and FPRL1R (FPR-like-1 receptor), which are encoded by the human genes FPR1 and FPRL1....