P Jeremy Wang
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Explore the profile of P Jeremy Wang including associated specialties, affiliations and a list of published articles.
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64
Citations
1984
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Recent Articles
11.
Ling L, Li F, Yang P, Oates R, Silber S, Kurischko C, et al.
Biol Reprod
. 2022 May;
107(1):157-167.
PMID: 35554494
Although hundreds of knockout mice show infertility as a major phenotype, the causative genic mutations of male infertility in humans remain rather limited. Here, we report the identification of a...
12.
Guan Y, Lin H, Leu N, Ruthel G, Fuchs S, Busino L, et al.
Nucleic Acids Res
. 2022 Apr;
50(9):5129-5144.
PMID: 35489071
Homeostasis of meiotic DNA double strand breaks (DSB) is critical for germline genome integrity and homologous recombination. Here we demonstrate an essential role for SKP1, a constitutive subunit of the...
13.
Yang F, Gervasi M, Orta G, Tourzani D, de la Vega-Beltran J, Ruthel G, et al.
Development
. 2021 Dec;
149(2).
PMID: 34919125
The CatSper cation channel is essential for sperm capacitation and male fertility. The multi-subunit CatSper complexes form highly organized calcium signaling nanodomains on flagellar membranes. Here, we report identification of...
14.
Liu R, Kasowitz S, Homolka D, Leu N, Shaked J, Ruthel G, et al.
Cell Rep
. 2021 Dec;
37(11):110110.
PMID: 34910909
Mechanisms driving the prolonged meiotic prophase I in mammals are poorly understood. RNA helicase YTHDC2 is critical for mitosis to meiosis transition. However, YTHDC2 is highly expressed in pachytene cells....
15.
Chotiner J, Leu N, Xu Y, Wang P
Biol Reprod
. 2021 Dec;
106(3):382-384.
PMID: 34850816
No abstract available.
16.
17.
Yin H, Kang Z, Zhang Y, Gong Y, Liu M, Xue Y, et al.
Nucleic Acids Res
. 2021 May;
49(9):5106-5123.
PMID: 33939832
The transition from meiotic spermatocytes to postmeiotic haploid germ cells constitutes an essential step in spermatogenesis. The epigenomic regulatory mechanisms underlying this transition remain unclear. Here, we find a prominent...
18.
Guan Y, Keeney S, Jain D, Wang P
PLoS Genet
. 2021 Feb;
17(2):e1009265.
PMID: 33635934
Piwi-interacting RNAs (piRNAs) play critical roles in protecting germline genome integrity and promoting normal spermiogenic differentiation. In mammals, there are two populations of piRNAs: pre-pachytene and pachytene. Transposon-rich pre-pachytene piRNAs...
19.
Li M, Feng H, Lin Z, Zheng J, Liu D, Guo R, et al.
J Genet Genomics
. 2020 Nov;
47(8):451-465.
PMID: 33250349
Meiosis is a specialized cell division for producing haploid gametes in sexually reproducing organisms. In this study, we have independently identified a novel meiosis protein male meiosis recombination regulator (MAMERR)/4930432K21Rik...
20.
Guo R, Xu Y, Leu N, Zhang L, Fuchs S, Ye L, et al.
Nucleic Acids Res
. 2020 Nov;
48(21):12219-12233.
PMID: 33166385
Meiotic recombination enables reciprocal exchange of genetic information between parental chromosomes and is essential for fertility. MEIOB, a meiosis-specific ssDNA-binding protein, regulates early meiotic recombination. Here we report that the...