Mengcheng Luo
Overview
Explore the profile of Mengcheng Luo including associated specialties, affiliations and a list of published articles.
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Articles
42
Citations
621
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Recent Articles
1.
Qu W, Xu Y, Yang J, Shi H, Wang J, Yu X, et al.
Acta Biochim Biophys Sin (Shanghai)
. 2024 Oct;
PMID: 39420836
Berberine (BBR) is used to treat diarrhea clinically. However, its reproductive toxicity is unclear. This study aims to investigate the impact of BBR on the male reproductive system. Intragastric BBR...
2.
Chen Z, Liu C, Qu W, Han Y, Zhu X, Li Z, et al.
Andrology
. 2024 Oct;
PMID: 39363403
Background: The PWWP domain-containing proteins are involved in chromatin-associated biological processes, including transcriptional regulation and DNA repair, and most of them are significant for gametogenesis and early embryonic development in...
3.
Li J, Wu P, Cao Z, Huang G, Lu Z, Yan J, et al.
Cell Rep
. 2024 Feb;
43(2):113765.
PMID: 38358884
The increasing emergence of Cas9 variants has attracted broad interest, as these variants were designed to expand CRISPR applications. New Cas9 variants typically feature higher editing efficiency, improved editing specificity,...
4.
Qu W, Yu X, Shi H, Chen Z, Luo M
Front Cell Dev Biol
. 2024 Feb;
12:1372799.
PMID: 38357001
No abstract available.
5.
Liu C, Wang Q, Gu L, Wang X, Yin Y, Huang T, et al.
Curr Biol
. 2023 Jul;
33(16):3371-3388.e7.
PMID: 37494937
The molecular mechanism underlying asymmetric axonemal complexes in sperm flagella is still largely unknown. Here, we showed that the knockout of the coiled-coil domain-containing 176 (CCDC176) in mice led to...
6.
Liu C, Wang L, Li Y, Guo M, Hu J, Wang T, et al.
Nucleic Acids Res
. 2023 Jun;
51(14):7357-7375.
PMID: 37378420
DNA-RNA hybrids play various roles in many physiological progresses, but how this chromatin structure is dynamically regulated during spermatogenesis remains largely unknown. Here, we show that germ cell-specific knockout of...
7.
The DOT1L-MLLT10 complex regulates male fertility and promotes histone removal during spermiogenesis
Lin H, Cossu I, Leu N, Deshpande A, Bernt K, Luo M, et al.
Development
. 2023 Apr;
150(9).
PMID: 37082953
Histone modifications regulate chromatin remodeling and gene expression in development and diseases. DOT1L, the sole histone H3K79 methyltransferase, is essential for embryonic development. Here, we report that DOT1L regulates male...
8.
Xu Y, Chen Z, Wu P, Qu W, Shi H, Cheng M, et al.
Acta Biochim Biophys Sin (Shanghai)
. 2022 Nov;
55(1):154-161.
PMID: 36331299
MEIOB is a vital protein in meiotic homologous recombination and plays an indispensable role in human gametogenesis. In mammals, MEIOB and its partner SPATA22 form a heterodimer, ensuring their effective...
9.
Chen Z, Xu Y, Ma D, Li C, Yu Z, Liu C, et al.
Front Physiol
. 2022 Oct;
13:948965.
PMID: 36277211
The centrosome regulates mammalian meiosis by affecting recombination, synapsis, chromosome segregation, and spermiogenesis. Cep72 is one of the critical components of the centrosome. However, the physiological role of Cep72 in...
10.
Liu R, Yun Y, Shu W, Wang X, Luo M
Front Genet
. 2022 Sep;
13:1002458.
PMID: 36081991
No abstract available.