P G Baraldi
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Explore the profile of P G Baraldi including associated specialties, affiliations and a list of published articles.
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80
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Recent Articles
1.
Gordaliza M, Baraldi P
Curr Med Chem
. 2013 Apr;
20(22):2798-811.
PMID: 23597202
Agelasines, asmarines and related compounds are natural products with a hybrid terpene-purine structure isolated from numerous genera of sponges (Agela sp, Raspailia sp). Nuttingins and malonganenones are tetraprenylated purine alkaloids...
2.
Romagnoli R, Baraldi P, Tabrizi M, Gessi S, Borea P, Merighi S
Curr Med Chem
. 2010 Aug;
17(30):3488-502.
PMID: 20738250
Adenosine is an important autocoid, exerting its physiological effects on the human body by activation of four different G-protein-coupled-receptors (GPCRs) classified as A(1), A(2A), A(2B), and A(3). These receptors are...
3.
Andre E, Gatti R, Trevisani M, Preti D, Baraldi P, Patacchini R, et al.
Br J Pharmacol
. 2009 Oct;
158(6):1621-8.
PMID: 19845671
Background And Purpose: The transient receptor potential ankyrin receptor 1 (TRPA1) is a cation channel, co-expressed with the pro-tussive transient receptor potential vanilloid type 1 (TRPV1) channel in primary sensory...
4.
Baraldi P, Spalluto G, Cacciari B, Romagnoli R, Setchell K
J Med Food
. 2009 Mar;
2(3-4):99-102.
PMID: 19281357
Pharmacokinetic and metabolic studies of phytoestrogens of the isoflavone class have been hampered by the lack of suitable stable-isotope-labeled analogs. A method for preparation of a [(13)C]-labeled analog of daidzein...
5.
Baraldi P, Guarneri M, Bader S, Zanotti F, Manfredini S, Spalluto G, et al.
Int J Cosmet Sci
. 2009 Feb;
17(4):147-56.
PMID: 19245483
Summary Diazoles have attracted considerable attention for a long time owing to their potentially interesting chemical, biochemical, and medicinal properties. We have reported the synthesis and in vitro antibacterial activity...
6.
Gessi S, Varani K, Merighi S, Morelli A, Ferrari D, Leung E, et al.
Br J Pharmacol
. 2001 Aug;
134(1):116-26.
PMID: 11522603
1. The present work was devoted to the study of A3 adenosine receptors in Jurkat cells, a human leukemia line. 2. The A3 subtype was found by means of RT-PCR...
7.
Baraldi P, Cacciari B, Moro S, Romagnoli R, Ji Xd , Jacobson K, et al.
J Med Chem
. 2001 Aug;
44(17):2735-42.
PMID: 11495585
A series of pyrazolotriazolopyrimidines was previously reported to be highly potent and selective human A(3) adenosine receptor antagonists (Baraldi et al. J. Med. Chem. 2000, 43, 4768-4780). A derivative having...
8.
Baraldi P, Balboni G, Pavani M, Spalluto G, Tabrizi M, Clercq E, et al.
J Med Chem
. 2001 Jul;
44(16):2536-43.
PMID: 11472207
We have synthesized and evaluated a series of hybrids, denoted 22--27, for in vitro cytotoxic activity against a variety of cancer cell lines. These hybrids represent a molecular combination of...
9.
Manfredini S, Baraldi P, Durini E, Porcu L, Angusti A, Vertuani S, et al.
Bioorg Med Chem Lett
. 2001 Jun;
11(10):1329-32.
PMID: 11392548
Highly selective arabinofuranosyl nucleosides, which inhibit the mitochondrial thymidine kinase (TK-2) without affecting the closely related herpes simplex virus type 1 thymidine kinase (HSV-1 TK), varicella-zoster virus thymidine kinase (VZV-TK),...
10.
Ongini E, Monopoli A, Cacciari B, Baraldi P
Farmaco
. 2001 May;
56(1-2):87-90.
PMID: 11347973
In the early 1990s it became clear that the A2A adenosine receptor had characteristics that made it distinct from the other A1, A2B and A3 adenosine receptors. Great progress has...