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Il Farmaco

Il Farmaco is a scientific journal, published by Elsevier since 1989 in English, French and Italian. The journal's country of origin is France and its primary focus areas are pharmacology and chemistry.

Details
Abbr. Farmaco
Publisher Elsevier
Start 1989
End 2005
Frequency Monthly
p-ISSN 0014-827X
e-ISSN 1879-0569
Country France
Languages English
French
Italian
Specialties Pharmacology
Chemistry
Recent Articles
1.
Zadrozna I, Kurkowska J, Kruszewska H
Farmaco . 2005 Oct; 60(11-12):948-54. PMID: 16243323
The salts, 2-methyl-5,5-disubstituted 4,5-dihydroisoxazolium methylsulfates comprising various substituents at the C-3 carbon atom were subjected to transformations. The structure of applied compounds permitted to monitor the effect of this factor...
2.
Yildiz A, Okyar A, Baktir G, Araman A, Ozsoy Y
Farmaco . 2005 Oct; 60(11-12):919-24. PMID: 16243322
In this study, heparin-loaded microspheres having smooth surface and small particle size were designed in order to provide the absorption of heparin through nasal mucosa. For this purpose, microspheres at...
3.
Berk B, Akgun H, Erol K, Sirmagul B, Gao Z, Jacobson K
Farmaco . 2005 Oct; 60(11-12):974-80. PMID: 16243321
The synthesis and structure determination of 8-aryl /alkyl aryl 1, 3-dimethyl-3, 7-dihydropurin-2, 6-dione derivatives (1-13), was carried out in this study. Bronchodilator activity is investigated using isolated guinea-pig tracheal strips,...
4.
Sharma P, Varma M, Chawla H, Panchagnula R
Farmaco . 2005 Oct; 60(11-12):874-83. PMID: 16243320
The present investigation attempts to increase intestinal permeability and hence absorption of biopharmaceutic classification system (BCS) Class III (cefotaxime sodium (CX)) and Class IV (cyclosporin A (CSA)) drugs by employing...
5.
Bezerra N, De Oliveira S, Srivastava R, Da Silva J
Farmaco . 2005 Oct; 60(11-12):955-60. PMID: 16242685
A simple, convenient and straightforward synthesis of 3-aryl-1,2,4-oxadiazoles 4a-f from arylamidoximes 1a-f and palmitic acid 2 is described. Compounds 4a-f are non-lethal in mice at four times the therapeutic dose...
6.
Zentz F, Labia R, Sirot D, Faure O, Grillot R, Valla A
Farmaco . 2005 Oct; 60(11-12):944-7. PMID: 16239002
A series of dithiines were synthesized by cyclization of 4-(alkylamino)-4-oxobutanoic acids under the action of SOCl2. Their in vitro antibacterial and antifungal activities have been evaluated against reference strains and...
7.
Venugopal K, Saha R
Farmaco . 2005 Oct; 60(11-12):906-12. PMID: 16226753
New, simple and cost effective UV-spectrophotometric methods were developed for the estimation of gatifloxacin in bulk and pharmaceutical formulations. Gatifloxacin was estimated at 286 nm in 100 mM phosphate buffer...
8.
Sharma P, Varma M, Chawla H, Panchagnula R
Farmaco . 2005 Oct; 60(11-12):884-93. PMID: 16226752
The objective of the present investigation was to evaluate an oral 'drug delivery' approach, which involves co-administration of absorption enhancers (AEs). The representative low permeable hydrophilic (biopharmaceutic classification system (BCS)...
9.
Viana Jr N, Moreira-Campos L, Vianna-Soares C
Farmaco . 2005 Oct; 60(11-12):900-5. PMID: 16226263
Formulation excipients can frequently affect the drug analysis in pharmaceuticals yielding background interference by ultraviolet spectrophotometry. Sample separation procedures to diminish such interferences are usually recommended as sample pre-treatment, however...
10.
Malinka W, Swiatek P, Filipek B, Sapa J, Jezierska A, Koll A
Farmaco . 2005 Oct; 60(11-12):961-8. PMID: 16223500
A series of new 4-arylpiperazine derivatives of isothiazolopyridine of Mannich base type and their non-4-arylpiperazine analogues (3 and 4) were synthesized and assayed as potential analgesic agents. Pharmacological assay demonstrated...