P D Jeffrey
Overview
Explore the profile of P D Jeffrey including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
87
Citations
3196
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Short M, Jeffrey P, Demirjian A, Margolies M
Protein Eng
. 2001 Jun;
14(4):287-96.
PMID: 11391021
We constructed Fab libraries of bacteriophage-displayed H:CDR3 mutants in the high-affinity anti-digoxin antibody 26-10 to determine structural constraints on affinity and specificity for digoxin. Libraries of mutant Fabs randomized at...
2.
Barton W, Lesniak J, Biggins J, Jeffrey P, Jiang J, Rajashankar K, et al.
Nat Struct Biol
. 2001 May;
8(6):545-51.
PMID: 11373625
Metabolite glycosylation is affected by three classes of enzymes: nucleotidylyltransferases, which activate sugars as nucleotide diphospho-derivatives, intermediate sugar-modifying enzymes and glycosyltransferases, which transfer the final derivatized activated sugars to aglycon...
3.
Jeffrey P, Tong L, Pavletich N
Genes Dev
. 2000 Dec;
14(24):3115-25.
PMID: 11124804
The cyclin-dependent kinases 4 and 6 (Cdk4/6) that drive progression through the G(1) phase of the cell cycle play a central role in the control of cell proliferation, and CDK...
4.
Schulman B, Carrano A, Jeffrey P, Bowen Z, Kinnucan E, Finnin M, et al.
Nature
. 2000 Dec;
408(6810):381-6.
PMID: 11099048
F-box proteins are members of a large family that regulates the cell cycle, the immune response, signalling cascades and developmental programmes by targeting proteins, such as cyclins, cyclin-dependent kinase inhibitors,...
5.
Krykbaev R, Liu W, Jeffrey P, Margolies M
J Biol Chem
. 2000 Nov;
276(11):8149-58.
PMID: 11060305
The heavy-chain CDR3 region of the high affinity (K(a) = 1.3 x 10(10) M(-)1) anti-digoxin monoclonal antibody 26-10 was modified previously to shift its specificity, by substitution of tryptophan 100...
6.
Zheng N, Wang P, Jeffrey P, Pavletich N
Cell
. 2000 Aug;
102(4):533-9.
PMID: 10966114
Ubiquitin-protein ligases (E3s) regulate diverse cellular processes by mediating protein ubiquitination. The c-Cbl proto-oncogene is a RING family E3 that recognizes activated receptor tyrosine kinases, promotes their ubiquitination by a...
7.
Bewley M, Jeffrey P, Patchett M, Kanyo Z, Baker E
Structure
. 1999 Apr;
7(4):435-48.
PMID: 10196128
Background: Arginase is a manganese-dependent enzyme that catalyzes the hydrolysis of L-arginine to L-ornithine and urea. In ureotelic animals arginase is the final enzyme of the urea cycle, but in...
8.
Jeffrey P, Bewley M, MacGillivray R, Mason A, WOODWORTH R, Baker E
Biochemistry
. 1998 Oct;
37(40):13978-86.
PMID: 9760232
Serum transferrin binds ferric ions in the bloodstream and transports them to cells, where they are released in a process involving receptor-mediated endocytosis. Iron release is believed to be pH...
9.
Russo A, Tong L, Lee J, Jeffrey P, Pavletich N
Nature
. 1998 Sep;
395(6699):237-43.
PMID: 9751050
The cyclin-dependent kinases 4 and 6 (Cdk4/6) that control the G1 phase of the cell cycle and their inhibitor, the p16INK4a tumour suppressor, have a central role in cell proliferation...
10.
Nourse A, Jeffrey P
Biophys Chem
. 1998 May;
71(1):21-34.
PMID: 9591358
An extensive study of the self-association patterns of zinc-free synthetic native and mutant (HB10D) platypus insulin in solution (pH = 7.0; I = 0.1 M; 25 degrees C) has been...