P C Trackman
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Explore the profile of P C Trackman including associated specialties, affiliations and a list of published articles.
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44
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1159
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Recent Articles
1.
Saxena D, Mahjour F, Findlay A, Mously E, Kantarci A, Trackman P
J Dent Res
. 2018 May;
97(11):1277-1284.
PMID: 29787337
Gingival overgrowth is a side effect of certain medications, including calcium channel blockers, cyclosporin A, and phenytoin. Phenytoin-induced gingival overgrowth is fibrotic. Lysyl oxidases are extracellular enzymes that are required...
2.
Herzog C, Berzins D, DenBesten P, Gregory R, Hargreaves K, Messer R, et al.
J Dent Res
. 2018 Jan;
97(5):483-491.
PMID: 29328868
For decades, dental schools in the United States have endured a significant faculty shortage. Studies have determined that the top 2 sources of dental faculty are advanced education programs and...
3.
Trackman P, Kantarci A
J Dent Res
. 2015 Feb;
94(4):540-6.
PMID: 25680368
Drug-induced gingival overgrowth is a tissue-specific condition and is estimated to affect approximately one million North Americans. Lesions occur principally as side-effects from phenytoin, nifedipine, or ciclosporin therapy in approximately...
4.
Bais M, Ozdener G, Sonenshein G, Trackman P
Oncogene
. 2014 Jun;
34(15):1928-37.
PMID: 24882580
Lysyl oxidase (LOX) is a multifunctional protein required for normal collagen and elastin biosynthesis and maturation. In addition, LOX has complex roles in cancer in which the lysyl oxidase propeptide...
5.
Kantarci A, Nseir Z, Kim Y, Sume S, Trackman P
J Dent Res
. 2011 Apr;
90(7):887-93.
PMID: 21483030
Gingival overgrowth tissues have thickened connective tissue stroma, sometimes accompanied by the increased presence of collagen fibers, thickened epithelia, and elongated rete pegs. We have previously shown that expression of...
6.
Palamakumbura A, Vora S, Nugent M, Kirsch K, Sonenshein G, Trackman P
Oncogene
. 2009 Jul;
28(38):3390-400.
PMID: 19597471
Enhanced RAS signaling and decreased androgen dependence of prostate cancer cells accompany poor clinical outcomes. Elevated autocrine fibroblast growth factors 2 (FGF-2) signaling promotes prostate cancer cell growth and survival....
7.
Pischon N, Maki J, Weisshaupt P, Heng N, Palamakumbura A, NGuessan P, et al.
Calcif Tissue Int
. 2009 May;
85(2):119-26.
PMID: 19458888
Lysyl oxidase (LOX) catalyzes cross-linking of elastin and collagen, which is essential for the structural integrity and function of bone tissue. The present study examined the role of Lox gene...
8.
Goncalves L, Oliveira G, Hurtado P, Feitosa A, Takiya C, Granjeiro J, et al.
J Periodontal Res
. 2008 Jul;
43(5):570-7.
PMID: 18624953
Objectives: Matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs) are known to be involved in the periodontal disease process. Results of in vivo MMPs and TIMPs gene expressions in the...
9.
Kantarci A, Augustin P, Firatli E, Sheff M, Hasturk H, Graves D, et al.
J Dent Res
. 2007 Aug;
86(9):888-92.
PMID: 17720861
Variations in the balance between cell proliferation and apoptosis could contribute to the etiology of gingival overgrowth. The aim of this study was to test the hypothesis that, in fibrotic...
10.
Kantarci A, Black S, Xydas C, Murawel P, Uchida Y, Yucekal-Tuncer B, et al.
J Pathol
. 2006 Jul;
210(1):59-66.
PMID: 16841303
Gingival overgrowth is a side effect of certain medications and occurs in non-drug-induced forms either as inherited (human gingival fibromatosis) or idiopathic gingival overgrowth. The most fibrotic drug-induced lesions develop...