P B McCray Jr
Overview
Explore the profile of P B McCray Jr including associated specialties, affiliations and a list of published articles.
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73
Citations
2608
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Recent Articles
1.
Sinn P, Hwang B, Li N, Ortiz J, Shirazi E, Parekh K, et al.
Gene Ther
. 2017 Sep;
24(10):674-679.
PMID: 28880020
Lentiviral vectors pseudotyped with the baculovirus envelope protein GP64 transduce primary cultures of human airway epithelia (HAE) at their apical surface. Our goal in this study was to harness a...
2.
Griffin M, Restrepo M, Abu-El-Haija M, Wallen T, Buchanan E, Rokhlina T, et al.
Gene Ther
. 2013 Nov;
21(2):123-30.
PMID: 24257348
Gene therapy offers the possibility to treat pancreatic disease in cystic fibrosis (CF), caused by mutations in the CF transmembrane conductance regulator (CFTR) gene; however, gene transfer to the pancreas...
3.
Banasik M, McCray Jr P
Gene Ther
. 2009 Oct;
17(2):150-7.
PMID: 19847206
Lentiviral vectors (LVs) offer the advantages of a large packaging capacity, broad cell tropism or specific cell-type targeting through pseudotyping, and long-term expression from integrated gene cassettes. However, transgene integration...
4.
Sinn P, Burnight E, McCray Jr P
Gene Ther
. 2009 Jul;
16(9):1059-65.
PMID: 19641533
Pulmonary gene therapy may ultimately cure diseases such as cystic fibrosis, alpha1-antitrypsin deficiency, lung cancer and pulmonary hypertension. Efficient expression of delivered genes in target cell types is essential for...
5.
Meyerholz D, Grubor B, Lazic T, Gallup J, de Macedo M, McCray Jr P, et al.
Vet Pathol
. 2006 Sep;
43(5):689-94.
PMID: 16966446
Preterm and young neonates are prone to inadequate surfactant production and are susceptible to respiratory distress syndrome characterized by alveolar damage and hyaline-membrane formation. Glucocorticoid therapy is commonly used in...
6.
Sinn P, Sauter S, McCray Jr P
Gene Ther
. 2005 Jul;
12(14):1089-98.
PMID: 16003340
Replication defective vectors derived from simple retroviruses or the more complex genomes of lentiviruses continue to offer the advantages of long-term expression, cell and tissue specific tropism, and large packaging...
7.
Premratanachai P, Joly S, Johnson G, McCray Jr P, Jia H, Guthmiller J
Oral Microbiol Immunol
. 2004 Feb;
19(2):111-7.
PMID: 14871351
This study evaluated the expression and regulation of beta-defensins DEFB-104 and the recently identified DEFB-105-14 in gingival keratinocytes. Keratinocytes from healthy subjects were exposed to cytokines, Escherichia coli lipopolysaccharide or...
8.
9.
Kalfa V, Jia H, Kunkle R, McCray Jr P, Tack B, Brogden K
Antimicrob Agents Chemother
. 2001 Oct;
45(11):3256-61.
PMID: 11600395
SMAP29, an ovine cathelicidin, was systematically altered to create a family of 23 related peptides for MIC and minimum bactericidal concentration determinations. SMAP28, SMAP29, and a derivative of SMAP29 called...
10.
Guthmiller J, Vargas K, Srikantha R, Schomberg L, Weistroffer P, McCray Jr P, et al.
Antimicrob Agents Chemother
. 2001 Oct;
45(11):3216-9.
PMID: 11600383
The effects of cathelicidins against oral bacteria and clinically important oral yeasts are not known. We tested the susceptibilities of Actinobacillus actinomycetemcomitans, Fusobacterium nucleatum, Porphyromonas gingivalis, Streptococcus sanguis, Candida krusei,...