Owen J Marshall
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Explore the profile of Owen J Marshall including associated specialties, affiliations and a list of published articles.
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26
Citations
1170
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Recent Articles
1.
Delandre C, McMullen J, Marshall O
Genetics
. 2025 Feb;
PMID: 39950543
Understanding how diverse cell types come together to form a functioning brain relies on the ability to specifically target these cells. This is often done using genetic tools such as...
2.
Lockyer J, Reading A, Vicenzi S, Zbela A, Viswanathan S, Delandre C, et al.
Proc Natl Acad Sci U S A
. 2024 Aug;
121(36):e2411846121.
PMID: 39190348
Optogenetic techniques provide genetically targeted, spatially and temporally precise approaches to correlate cellular activities and physiological outcomes. In the nervous system, G protein-coupled receptors (GPCRs) have essential neuromodulatory functions through...
3.
Xu C, Ramos T, Marshall O, Doe C
Elife
. 2024 Jan;
12.
PMID: 38193901
Notch signaling is an evolutionarily conserved pathway for specifying binary neuronal fates, yet how it specifies different fates in different contexts remains elusive. In our accompanying paper, using the lamina...
4.
Josserand M, Rubanova N, Stefanutti M, Roumeliotis S, Espenel M, Marshall O, et al.
Dev Cell
. 2023 Dec;
58(24):3048-3063.e6.
PMID: 38056452
Tissue homeostasis relies on rewiring of stem cell transcriptional programs into those of differentiated cells. Here, we investigate changes in chromatin occurring in a bipotent adult stem cells. Combining mapping...
5.
Rogers M, Marshall O, Secombe J
Development
. 2023 Oct;
150(21).
PMID: 37800333
Histone-modifying proteins play important roles in the precise regulation of the transcriptional programs that coordinate development. KDM5 family proteins interact with chromatin through demethylation of H3K4me3 as well as demethylase-independent...
6.
Zaytseva O, Mitchell N, Muckle D, Delandre C, Nie Z, Werner J, et al.
Development
. 2023 Jan;
150(2).
PMID: 36692218
The first characterised FUSE Binding Protein family member, FUBP1, binds single-stranded DNA to activate MYC transcription. Psi, the sole FUBP protein in Drosophila, binds RNA to regulate P-element and mRNA...
7.
Marshall O, Delandre C
Methods Mol Biol
. 2022 Feb;
2458:195-213.
PMID: 35103969
Targeted DamID (TaDa) is a means of profiling the binding of any DNA-associated protein cell-type specifically, including transcription factors, RNA polymerase, and chromatin-modifying proteins. The technique is highly sensitive, highly...
8.
Heng J, Viti L, Pugh K, Marshall O, Agostino M
J Neurochem
. 2022 Jan;
161(3):219-235.
PMID: 35083747
Mutations to genes that encode DNA-binding transcription factors (TFs) underlie a broad spectrum of human neurodevelopmental disorders. Here, we highlight the pathological mechanisms arising from mutations to TF genes that...
9.
Hatch H, Belalcazar H, Marshall O, Secombe J
Elife
. 2021 Mar;
10.
PMID: 33729157
Mutations in the lysine demethylase 5 (KDM5) family of transcriptional regulators are associated with intellectual disability, yet little is known regarding their spatiotemporal requirements or neurodevelopmental contributions. Utilizing the mushroom...
10.
Diaz-Torres A, Rosales-Nieves A, Pearson J, Santa-Cruz Mateos C, Marin-Menguiano M, Marshall O, et al.
Curr Biol
. 2021 Feb;
31(8):1744-1753.e5.
PMID: 33621481
Stem cells reside in specialized microenvironments or niches that balance stem cell proliferation and differentiation. The extracellular matrix (ECM) is an essential component of most niches, because it controls niche...