Ossia M Eichhoff
Overview
Explore the profile of Ossia M Eichhoff including associated specialties, affiliations and a list of published articles.
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18
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1782
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Recent Articles
11.
Widmer D, Cheng P, Eichhoff O, Belloni B, Zipser M, Schlegel N, et al.
Pigment Cell Melanoma Res
. 2012 Feb;
25(3):343-53.
PMID: 22336146
There is growing evidence that the metastatic spread of melanoma is driven not by a linear increase in tumorigenic aggressiveness, but rather by switching back and forth between two different...
12.
Eichhoff O, Weeraratna A, Zipser M, Denat L, Widmer D, Xu M, et al.
Pigment Cell Melanoma Res
. 2011 May;
24(4):631-42.
PMID: 21599871
Recent observations suggest that melanoma cells drive disease progression by switching back and forth between phenotypic states of proliferation and invasion. Phenotype switching has been linked to changes in Wnt...
13.
Zipser M, Eichhoff O, Widmer D, Schlegel N, Schoenewolf N, Stuart D, et al.
Pigment Cell Melanoma Res
. 2010 Dec;
24(2):326-33.
PMID: 21176117
Oncogenic mutations within the MAPK pathway are frequent in melanoma, and targeting of MAPK signaling has yielded spectacular responses in a significant number of patients that last for several months...
14.
Eichhoff O, Zipser M, Xu M, Weeraratna A, Mihic D, Dummer R, et al.
Melanoma Res
. 2010 Jun;
20(4):349-55.
PMID: 20526217
To date there is no effective therapy for metastatic melanoma and at the molecular level the disease progression is poorly understood. A recent study by our group led to the...
15.
Schlegel N, Eichhoff O, Hemmi S, Werner S, Dummer R, Hoek K
Pigment Cell Melanoma Res
. 2009 Apr;
22(4):445-53.
PMID: 19368689
Proliferative resistance to transforming growth factor beta (TGF-beta) is regarded as a critical turning point in the malignant progression of many cancer types. In melanoma this resistance is associated with...
16.
Hoek K, Eichhoff O, Widmer D, Dummer R
Pigment Cell Melanoma Res
. 2009 Jan;
22(1):6-7.
PMID: 19140883
No abstract available.
17.
Hoek K, Schlegel N, Eichhoff O, Widmer D, Praetorius C, Einarsson S, et al.
Pigment Cell Melanoma Res
. 2008 Dec;
21(6):665-76.
PMID: 19067971
Malignant melanoma is a chemotherapy-resistant cancer with high mortality. Recent advances in our understanding of the disease at the molecular level have indicated that it shares many characteristics with developmental...
18.
Hoek K, Eichhoff O, Schlegel N, Dobbeling U, Kobert N, Schaerer L, et al.
Cancer Res
. 2008 Feb;
68(3):650-6.
PMID: 18245463
Metastatic melanoma represents a complex and heterogeneous disease for which there are no therapies to improve patient survival. Recent expression profiling of melanoma cell lines identified two transcription signatures, respectively,...