Osamu Takeuchi
Overview
Explore the profile of Osamu Takeuchi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
292
Citations
35353
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Asano R, Okazawa M, Ishibashi T, Ding X, Ohta-Ogo K, Akaki K, et al.
Circ Rep
. 2025 Mar;
7(3):207-211.
PMID: 40066211
Background: Because Regnase-1, encoded by , suppresses the development of pulmonary arterial hypertension (PAH) by controlling pro-inflammatory cytokines, we aimed to identify variants in patients with PAH. Methods And Results:...
2.
Miyazaki K, Horie K, Watanabe H, Hidaka R, Hayashi R, Hayatsu N, et al.
Genes Dev
. 2025 Feb;
39(5-6):384-400.
PMID: 39904558
External signals from the thymic microenvironment and the activities of lineage-specific transcription factors (TFs) instruct T-cell versus innate lymphoid cell (ILC) fates. However, mechanistic insights into how factors such as...
3.
Pae S, Sedukhina A, Sugiyama R, Atanacio S, Ohara T, Ishii M, et al.
Sci Rep
. 2024 Dec;
14(1):31276.
PMID: 39732958
The overexpression of Polo-like kinase 1 (PLK1) is associated with poor clinical outcomes in various malignancies, making it an attractive target for anticancer therapies. Although recent studies suggest PLK1's involvement...
4.
Taninaka A, Kurokawa H, Kamiyanagi M, Takeuchi O, Matsui H, Shigekawa H
Nanomaterials (Basel)
. 2024 Dec;
14(23).
PMID: 39683251
We investigated stress fiber formation induced by photodynamic therapy (PDT) with porphylipoprotein (PLP) by observing actin filaments by super-resolution confocal microscopy and measuring the cellular elastic modulus by atomic force...
5.
Koyama S, Liu X, Koike Y, Hikino K, Koido M, Li W, et al.
Nat Genet
. 2024 Oct;
56(10):2027-2035.
PMID: 39363016
Human genetic variants are associated with many traits through largely unknown mechanisms. Here, combining approximately 260,000 Japanese study participants, a Japanese-specific genotype reference panel and statistical fine-mapping, we identified 4,423...
6.
Morimoto Y, Takada K, Nakano A, Takeuchi O, Watanabe K, Hirohara M, et al.
Cancer Chemother Pharmacol
. 2024 Sep;
94(6):763-774.
PMID: 39271497
Purpose: In our previous study, we found that the Chk1 inhibitor prexasertib enhances the antitumour effect of the oral anticancer drug S-1 against pancreatic cancer cells. In this study, we...
7.
Iwai N, Akaki K, Hia F, Li W, Yoshinaga M, Mino T, et al.
Nat Commun
. 2024 Jul;
15(1):5765.
PMID: 38982067
The ATP-dependent RNA helicase UPF1 plays a crucial role in various mRNA degradation pathways, most importantly in nonsense-mediated mRNA decay (NMD). Here, we show that UPF1 is upregulated during the...
8.
Ali T, Nguyen H, Abbas N, Takeuchi O, Akira S, Suzuki T, et al.
Int Immunol
. 2024 Apr;
36(9):439-450.
PMID: 38567483
Transforming growth factor-β-activated kinase 1 (TAK1) plays a pivotal role in innate and adaptive immunity. TAK1 is essential for the activation of mitogen-activated protein kinases (MAPKs) and nuclear factor (NF)-κB...
9.
Hoshino A, Oana Y, Ohi Y, Maeda Y, Omori M, Takada Y, et al.
Acta Cytol
. 2024 Mar;
68(2):145-152.
PMID: 38555634
Introduction: Cancer genome analysis using next-generation sequencing requires adequate and high-quality DNA samples. Genomic analyses were conventionally performed using formalin-fixed paraffin-embedded sections rather than cytology samples such as cell block...
10.
Matsui H, Sugamata M, Endo H, Suzuki Y, Takarabe Y, Yamaguchi Y, et al.
Cureus
. 2024 Mar;
16(2):e54919.
PMID: 38544617
Introduction Hand hygiene is an infection control measure for COVID-19 in our daily lives; however, the contamination levels of SARS-CoV-2 in the hands of healthy individuals remain unclear. Thus, we...