Osami Kanagawa
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Explore the profile of Osami Kanagawa including associated specialties, affiliations and a list of published articles.
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52
Citations
3200
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Recent Articles
1.
Villani A, Rozieres A, Bensaid B, Eriksson K, Mosnier A, Albert F, et al.
Sci Adv
. 2021 Mar;
7(12).
PMID: 33741590
Toxic epidermal necrolysis (TEN) is a life-threatening cutaneous adverse drug reaction. To better understand why skin symptoms are so severe, we conducted a prospective immunophenotyping study on skin and blood....
2.
Takegahara N, Kim H, Mizuno H, Sakaue-Sawano A, Miyawaki A, Tomura M, et al.
J Biol Chem
. 2015 Dec;
291(7):3439-54.
PMID: 26670608
Osteoclasts are specialized polyploid cells that resorb bone. Upon stimulation with receptor activator of nuclear factor-κB ligand (RANKL), myeloid precursors commit to becoming polyploid, largely via cell fusion. Polyploidization of...
3.
Kinjyo I, Qin J, Tan S, Wellard C, Mrass P, Ritchie W, et al.
Nat Commun
. 2015 Feb;
6:6301.
PMID: 25709008
The precise pathways of memory T-cell differentiation are incompletely understood. Here we exploit transgenic mice expressing fluorescent cell cycle indicators to longitudinally track the division dynamics of individual CD8(+) T...
4.
Kumar R, Bach M, Mainoldi F, Maruya M, Kishigami S, Jumaa H, et al.
Proc Natl Acad Sci U S A
. 2015 Jan;
112(5):E450-7.
PMID: 25609671
In mammals, VDJ recombination is responsible for the establishment of a highly diversified preimmune antibody repertoire. Acquisition of a functional Ig heavy (H) chain variable (V) gene rearrangement is thought...
5.
Kozono H, Matsushita Y, Ogawa N, Kozono Y, Miyabe T, Sekiguchi H, et al.
Biophys J
. 2015 Jan;
108(2):350-9.
PMID: 25606683
The major histocompatibility complex (MHC) class II protein can bind peptides of different lengths in the region outside the peptide-binding groove. Peptide-flanking residues (PFRs) contribute to the binding affinity of...
6.
Tomura M, Hata A, Matsuoka S, Shand F, Nakanishi Y, Ikebuchi R, et al.
Sci Rep
. 2014 Aug;
4:6030.
PMID: 25112380
Skin-derived dendritic cells (DCs) play a crucial role in the maintenance of immune homeostasis due to their role in antigen trafficking from the skin to the draining lymph nodes (dLNs)....
7.
Tomura M, Sakaue-Sawano A, Mori Y, Takase-Utsugi M, Hata A, Ohtawa K, et al.
PLoS One
. 2013 Sep;
8(9):e73801.
PMID: 24066072
A transgenic mouse line expressing Fucci (fluorescent ubiquitination-based cell-cycle indicator) probes allows us to monitor the cell cycle in the hematopoietic system. Two populations with high and low intensities of...
8.
Suan D, Hampton H, Tomura M, Kanagawa O, Chtanova T, Phan T
Methods Cell Biol
. 2013 Jan;
113:311-23.
PMID: 23317908
Commercial two-photon microscope systems incorporating turnkey ultrafast lasers have made the technology more user-friendly and accessible to nonspecialized biology laboratories. This has been accompanied by the development of an exciting...
9.
Bromley S, Yan S, Tomura M, Kanagawa O, Luster A
J Immunol
. 2012 Dec;
190(3):970-6.
PMID: 23255361
Several populations of memory T cells have been described that differ in their migration and function. In this study, we have identified a unique subset of memory T cells, which...
10.
Kotani M, Kikuta J, Klauschen F, Chino T, Kobayashi Y, Yasuda H, et al.
J Immunol
. 2012 Dec;
190(2):605-12.
PMID: 23241888
Osteoclasts are bone-resorbing polykaryons differentiated from monocyte/macrophage-lineage hematopoietic precursors. It remains unclear whether osteoclasts originate from circulating blood monocytes or from bone tissue-resident precursors. To address this question, we combined...